Results 61 to 70 of about 8,957,712 (279)

SpotMe Emergency Location Service [PDF]

open access: yes, 2018
This document delves into our disaster relief application that allows people who are helpless due to a natural disaster to find a way out and get help. The purpose of this document is to explain how the application works, but more specifically the design
Bhimjiyani, Kunal   +2 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Epcoritamab induces potent anti-tumor activity against malignant B-cells from patients with DLBCL, FL and MCL, irrespective of prior CD20 monoclonal antibody treatment

open access: yesBlood Cancer Journal, 2021
Epcoritamab (DuoBody-CD3xCD20, GEN3013) is a novel bispecific IgG1 antibody redirecting T-cells toward CD20+ tumor cells. Here, we assessed the preclinical efficacy of epcoritamab against primary tumor cells present in the lymph node biopsies from newly ...
Hilma J. van der Horst   +12 more
doaj   +1 more source

Location Privacy in Spatial Crowdsourcing

open access: yes, 2017
Spatial crowdsourcing (SC) is a new platform that engages individuals in collecting and analyzing environmental, social and other spatiotemporal information.
A Liu   +9 more
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Autophagy-enhancing ATG16L1 polymorphism is associated with improved clinical outcome and T-cell immunity in chronic HIV-1 infection

open access: yesNature Communications
Chronic HIV-1 infection is characterized by T-cell dysregulation that is partly restored by antiretroviral therapy. Autophagy is a critical regulator of T-cell function.
Renée R. C. E. Schreurs   +8 more
doaj   +1 more source

Automatic lightning location system [PDF]

open access: yes, 1972
Hyperbolic triangulation method was used for locating lightning storm path and position from VHF lightning charge emissions. Possible applications in electric power companies, forest fire lookout centers, airports, and pipeline companies are ...
Holdsworth, T., March, D. N.
core   +1 more source

Location-domination in line graphs

open access: yes, 2016
A set $D$ of vertices of a graph $G$ is locating if every two distinct vertices outside $D$ have distinct neighbors in $D$; that is, for distinct vertices $u$ and $v$ outside $D$, $N(u) \cap D \neq N(v) \cap D$, where $N(u)$ denotes the open neighborhood
Foucaud, Florent, Henning, Michael A.
core   +3 more sources

Facility location with double-peaked preference [PDF]

open access: yes, 2015
We study the problem of locating a single facility on a real line based on the reports of self-interested agents, when agents have double-peaked preferences, with the peaks being on opposite sides of their locations.
Filos-Ratsikas, Aris   +3 more
core   +4 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

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