Results 91 to 100 of about 1,010,894 (298)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Group colocation behavior in technological social networks.
PLoS ONE, 2014 We analyze two large datasets from technological networks with location and social data: user location records from an online location-based social networking service, and anonymized telecommunications data from a European cellphone operator, in order to
Chloë Brown +4 more
doaj +1 more source
Place-Type Detection in Location-Based Social Networks
Proceedings of the 28th ACM Conference on Hypertext and Social Media, 2017 Determining the type of places in location-based social networks will contribute to the success of various downstream tasks such as POI recommendation, location search, automatic place name database creation, and data cleaning. In this paper, we propose a multi-objective ensemble learning framework that (i) allows the accurate tagging of places into ...
Hasanuzzaman, Mohammed, Way, Andy
openaire +1 more source
Latent Space Model for Multi-Modal Social Data
, 2015 With the emergence of social networking services, researchers enjoy the increasing availability of large-scale heterogenous datasets capturing online user interactions and behaviors.
Al Zamal F. +9 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
RcDT: Privacy Preservation Based on R-Constrained Dummy Trajectory in Mobile Social Networks
IEEE Access, 2019 The boom of mobile devices and location-based services (LBSs) greatly enriches the mobile social network (MSN) applications, which bring convenience to our daily life and, meanwhile, raise serious privacy concerns due to the potential disclosure risk of ...
Jinquan Zhang +3 more
doaj +1 more source
Users Location Prediction in Location-based Social Networks
Electronic Workshops in Computing, 2015 The wealth of user-generated data in Location-Based Social Networks (LBSNs) has opened new opportunities for researchers to model and understand human mobile behaviour, including predicting where they are most likely to check-in next. In this paper, we propose a model that leverages the use of Global Temporal Preferences and Spatial Correlation, to ...
openaire +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Exchanging registered users' submitting reviews towards trajectory privacy preservation for review services in Location-Based Social Networks. [PDF]
PLoS One, 2021 Wang Y +7 more
europepmc +1 more source