Results 41 to 50 of about 601,506 (267)

Temporary Facility Location Problem in Humanitarian Logistics: A Systematic Literature Review

open access: yesLogistics
Background: Facility location is a key challenge in humanitarian logistics, particularly in disaster response, where rapid and efficient resource deployment is crucial.
María Fernanda Carnero Quispe   +3 more
doaj   +1 more source

Anchored Hyperplane Location Problems [PDF]

open access: yesDiscrete and Computational Geometry, 2003
The paper considers a restricted version of a hyperplane location problem in \(\mathbb R^n\): The anchored hyperplane location problem consists of locating a hyperplane in \(\mathbb R^n\) that passes through a given set of points \(P\) while it minimizes at the same time the median objective or the center objective, respectively, with respect to a ...
openaire   +5 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On MILP Models for the OWA Optimization

open access: yesJournal of Telecommunications and Information Technology, 2012
The problem of aggregating multiple outcomes to form overall objective functions is of considerable importance in many applications. The ordered weighted averaging (OWA) aggregation uses the weights assigned to the ordered values (i.e., to the largest ...
Włodzimierz Ogryczak, Paweł Olender
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Optimizing Cross-Dock Terminal Location Selection: A Multi-Step Approach Based on CI-DEA–IDOCRIW–MABAC for Enhanced Supply Chain Efficiency—A Case Study

open access: yesMathematics
Thedistribution of products stands out as one of the pivotal activities for logistics companies in recent years, particularly in the aftermath of the COVID-19 pandemic and other geopolitical events.
Jingya Wang   +3 more
doaj   +1 more source

An impact of some parameters on correctness of the location problem solution [PDF]

open access: yesTransport Problems, 2008
This paper deals with the modifications of customer demands and with the impact of modifications of customer demands on the location of supply centers. The solution of the location problem with exactly p location is sought.
Marta JANÁČKOVÁ   +1 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Multi-Objective Location Problem for Bank Branches

open access: yesIEEE Access, 2023
Although current technologies allow simple online banking transactions, it is vital to guarantee access to bank branches both for customers and businesses.
Elizabeth Montero   +3 more
doaj   +1 more source

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