Results 41 to 50 of about 601,506 (267)
Temporary Facility Location Problem in Humanitarian Logistics: A Systematic Literature Review
Background: Facility location is a key challenge in humanitarian logistics, particularly in disaster response, where rapid and efficient resource deployment is crucial.
María Fernanda Carnero Quispe +3 more
doaj +1 more source
Anchored Hyperplane Location Problems [PDF]
The paper considers a restricted version of a hyperplane location problem in \(\mathbb R^n\): The anchored hyperplane location problem consists of locating a hyperplane in \(\mathbb R^n\) that passes through a given set of points \(P\) while it minimizes at the same time the median objective or the center objective, respectively, with respect to a ...
openaire +5 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
On MILP Models for the OWA Optimization
The problem of aggregating multiple outcomes to form overall objective functions is of considerable importance in many applications. The ordered weighted averaging (OWA) aggregation uses the weights assigned to the ordered values (i.e., to the largest ...
Włodzimierz Ogryczak, Paweł Olender
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Thedistribution of products stands out as one of the pivotal activities for logistics companies in recent years, particularly in the aftermath of the COVID-19 pandemic and other geopolitical events.
Jingya Wang +3 more
doaj +1 more source
An impact of some parameters on correctness of the location problem solution [PDF]
This paper deals with the modifications of customer demands and with the impact of modifications of customer demands on the location of supply centers. The solution of the location problem with exactly p location is sought.
Marta JANÁČKOVÁ +1 more
doaj
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Multi-Objective Location Problem for Bank Branches
Although current technologies allow simple online banking transactions, it is vital to guarantee access to bank branches both for customers and businesses.
Elizabeth Montero +3 more
doaj +1 more source

