Results 61 to 70 of about 2,447,655 (294)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Geophysical Research LettersDecadal predictions are affected by initialization shocks and drift, typically diagnosed in ocean circulation or temperature. It is not known, however, to what extent the drift can affect atmospheric dynamics.
Rashed Mahmood +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
MathematicsDetecting small location shifts in stochastic processes is a fundamental problem in sequential statistical monitoring. Classical procedures such as Shewhart-type schemes, exponentially weighted moving average (EWMA), and cumulative sum (CUSUM) methods ...
Elif Kozan
doaj +1 more source
World Manufacturing Industry: Structural and Spatial Shifts [PDF]
Annals of the University of Bucharest: Geography Series, 2012 The article estimates countries’ and regions’ posit ions on the world ranking hierarchy in the manufacturing industry. The research is focusing on the characteristic of structural and spatial shift s of the world manufacturing ...
IRINA RODIONOVA
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Attention shifts to more complex locations with experience
, 2021 Our environments are saturated with learnable information. What determines which of this information gets prioritized for limited attentional resources? While previous studies suggest that learners prefer medium complexity information, here we argue that what counts as medium should change as someone learns an input's structure.
Tess Forest, Noam Siegelman, Amy Finn
openaire +2 more sources
Processing of Unattended Emotional Facial Expressions: Correlates of Visual Field Bias in Women
Frontiers in Neuroscience, 2017 Lateralization in emotional processing is a matter of ongoing debate. Various factors can influence lateralized emotional processing, including stimulus location, emotional valence, and gender.
Dina Wittfoth +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source