Results 81 to 90 of about 2,447,655 (294)

Intelligent Location Models for Next Generation Location-based Services

open access: yes, 2007
To become truly ubiquitous, next generation location-based services (LBS) will have to rely on mobile platforms upon which multiple sensors and measurement systems have been integrated to provide continuous, three-dimensional positioning and orientation.
Winter, Stephan   +2 more
core   +4 more sources

Alternative Nonparametric Test and Sample Size Procedures for the Comparison of Several Location Shifts

open access: yesJournal of Statistical Theory and Applications (JSTA)
The Kruskal–Wallis test is widely recommended as a nonparametric counterpart to the ANOVA F procedure for comparing more than two treatments. However, the associated asymptotic chi-square distribution tends to be conservative, especially for small sample
Show-Li Jan, Gwowen Shieh
doaj   +1 more source

Analyzing temporal mobility pattern shifts: Dynamic origin–destination estimation from aggregated mobile phone location data

open access: yesTransportation Research Interdisciplinary Perspectives
Understanding the dynamic shifts in population distribution is crucial for comprehending spatiotemporal mobility patterns and phenomena at the urban scale.
Alvin Noviansyah   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Incorporating Population Dynamics in the Context of Earthquake Shelter Location-Allocation Analysis

open access: yesEuropean Journal of Geography
Location-allocation is a widely used approach to optimally select earthquake shelters and efficiently allocate the population in case of an emergency.
Marios Batsaris
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Impaired perceptual memory of locations across gaze-shifts in patients with unilateral spatial neglect [PDF]

open access: yes, 2007
Right-hemisphere lesions often lead to severe disorders in spatial awareness and behavior, such as left hemispatial neglect. Neglect involves not only pathological biases in attention and exploration, but also deficits in internal representations of ...
Schwartz, S.   +19 more
core   +1 more source

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