Results 61 to 70 of about 1,471 (237)

Rytą or ryte? Vakarą or vakare? A corpus analysis of Lithuanian time expressions denoting parts of the day

open access: yesKalbotyra
This paper aims to reveal differences between the competing accusative and locative forms of Lithuanian temporal expressions denoting parts of the day (rytas ‘morning’, diena ‘day’, vakaras ‘evening’, naktis ‘night’).
Nina Kapušová
doaj   +3 more sources

Two ways of encoding location in Greek: Locative applicatives and prepositions

open access: yesGlossa, 2016
Cross-linguistically, oblique theta roles such as location can be encoded by both adpositions and applicative morphemes. In this paper we argue that Standard Modern Greek (SMG), a language that encodes location primarily with prepositions, has a set of ...
Evangelia Daskalaki, Marios Mavrogiorgos
doaj   +2 more sources

Filtered in/filtered out: Locative media and social accessibility in urban spaces

open access: yesStudies in Communication Sciences, 2021
Social accessibility involves the capacity of a person to be reached by other people, typically through established social networks. Locative media provide new complications to the issue of social accessibility in urban spaces. They do not connect people
Darryl A. Pieber
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Invisible Locative Media: Key Considerations at the Nexus of Place and Digital Journalism

open access: yesMedia and Communication, 2019
Mobility and location-awareness are pervasive and foundational elements of contemporary communication systems, and a descriptive term to synthesize them, “locative media”, has gained widespread use throughout mobile media and communication research. That
Ivar John Erdal   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Internal location in Mandarin Chinese

open access: yesLinguistics
This paper illustrates the crucial role of “internal locatives” (Maienborn, C. 2001. On the position and interpretation of locative modifiers. Natural Language Semantics 9(2).
Tham Shiao Wei
doaj   +1 more source

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