Results 101 to 110 of about 1,592 (288)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The syntax of locative inversion: The preverbal locative NP in Lexical Functional Grammar
, 2018 Locative inversion construction in Setswana, as in other Bantu languages, defies straightforward analysis in the sense that the preverbal locative NP does not pass the subject hood test, while the post-verbal NP shows features atypical of objects. In the
Morapedi, Setumile
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The non-dominant hand perseveration and movement in SZJ locative constructions
, 2018 In sign languages, signers habitually encode the relations between locative arguments with a complex predicate consisting of several independent morphemes, as shown by Pfau and Aboh (2012) for Sign Language of the Netherlands.
Pavlič, Matic
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2013 Esta tese se concentra sobre os debates referentes à relação entre as construções locativas, existenciais e possessivas nas línguas do mundo, dando especial atenção para o caso particular das línguas bantas, para as quais o entendimento mais completo da ...
Paulo Jeferson Pilar Araújo +1 more
core +1 more source
Sentence comprehension test for Russian: A tool to assess syntactic competence. [PDF]
Front Psychol, 2023 Chernova D, Novozhilov A, Slioussar N.
europepmc +1 more source
English Locative Inversion: Grammatical Interfaces and Constructions
Annual Meeting of the Berkeley Linguistics Society, 2003 Proceedings of the Twenty-Ninth Annual Meeting of the Berkeley Linguistics Society: General Session and Parasession on Phonetic Sources of Phonological Patterns: Synchronic and Diachronic Explanations (2003)
openaire +2 more sources
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Structure and interpretation in Swahili existential constructions
, 2013 Swahili has two existential constructions, one formed with a possessive copula and a locative subject marker (locative-possessive constructions), the other formed with a locative copula and a non-locative subject marker agree- ing with the theme argument
Marten, Lutz
core