Results 81 to 90 of about 1,592 (288)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Frontiers in Psychology, 2018 The current study focuses on the acquisition of classifier constructions in Hong Kong Sign Language (HKSL) by a group of Deaf children of hearing parents, aided or implanted.
Gladys W. L. Tang, Jia Li
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2023 The present paper provides a methodological case study on how underlying incipient grammar change might be discerned even when frequencies of the incoming variant are apparently marginal and stable.
Matti Marttinen Larsson +2 more
core +1 more source
Locative sentences and related constructions in Catalan: "ésser / haver" alternation
Anuario del Seminario de Filología Vasca "Julio de Urquijo", 1997 -
Gemma Rigau
doaj +1 more source
The Construction of Locative Situations: the Production of Agency in Locative Media Art Practice
, 2012 This thesis is a practice led enquiry into Locative Media (LM) which argues that this emergent art practice has played an influential role in the shaping of locative technologies in their progression from new to everyday technologies. The research traces LM to its origins at the Karosta workshops, reviews the stated objectives of early practitioners ...
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
LanguagesPresentational constructions, i.e., structures which introduce an event into the universe of discourse, raise the question of what it means for a predication to be entirely new in information structural terms.
Delia Bentley, Francesco Maria Ciconte
doaj +1 more source
Studia Humanitatis, 2021 The article studies the features of the spatial subcategory of locativity in the terminology of the biotechnology sphere and the identification of a set of tools in the English language that serve to express this subcategory.
Syrotina Olena Oleksiyivna
doaj