Results 71 to 80 of about 1,592 (288)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

The locative-applicative in Eleme [PDF]

open access: yes, 2014
The Eleme locative-applicative =rũ is a non-canonical applicative that demonstrates morphosyntactic properties commonly associated with clitics. It is employed in one of two functions: (i) to indicate an increase in the transitivity of a clause and ...
Bond, O
core   +2 more sources

Evolution des prépositions et emplois locatifs en français depuis le XVe siècle - sintaxe et conceptualisation de l'espace? [PDF]

open access: yesLinguística, 2008
The paper first expounds the concept of strong vs weak locativity defined by means of both syntactic and conceptual features and exemplified by various locative prepositional groups (en poche vs dans la poche).
Jaroslav Stichauer
doaj  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Adpositions locatives en français de Côte d’Ivoire, en dioula et en baoulé

open access: yesCorela, 2006
The analysis proposed here compares certain locative constructions in Ivory Coast French, specifically Jula and Bawle (two Ivorian languages), in order to examine the function of locative adpositions from a contrastive point of view.
Akissi Béatrice Boutin
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The syntax of existential sentences in Serbian

open access: yes, 2008
Freeze (1992) argued on the basis of data from several different languages that there is a close relationship between existential sentences (stating the existence of an entity) and locative sentences (stating the location of an entity).
Milicevic, Nataša, Hartmann, Jutta M.
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Locative inversion in Cuwabo

open access: yes, 2014
This paper proposes a detailed description of locative inversion (LI) constructions in Cuwabo, in terms of morphosyntactic properties and thematic restrictions.
Guérois, Rozenn
core   +1 more source

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