Results 61 to 70 of about 1,122 (295)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On null spatial Ps and their arguments

open access: yesCatalan Journal of Linguistics, 2010
This paper investigates the phenomenon of null spatial Ps, focusing primarily on Greek where these are most widely attested. It is demonstrated that only locatives (of the type that do not denote containment), as well as directional goal Ps, are able to ...
Ahonto Terzi
doaj   +1 more source

Tswana locatives and their status in the inversion construction

open access: yes, 2011
Several articles published in the last decade have demonstrated that, in several Sotho-Tswana (S30) and Nguni (S40) languages, locative marking has ceased to be integrated into the noun class system, and preverbal locatives in inversion constructions do ...
Denis Creissels, Creissels, Denis
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

An experimental study of Children’s acquisition of Mandarin recursive locatives

open access: yesJournal of Child Language Acquisition and Development
Recursion is widely regarded as a defining property of human language, yet its acquisition remains uneven across domains and languages. While previous research has focused primarily on recursive possessives and prepositional phrases, recursive locative ...
Xiaoyi Wang, Chenxi Fu, Caimei Yang
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Locative NP’s, Locative Suffixes, and Grammatical Relations

open access: yesAnnual Meeting of the Berkeley Linguistics Society, 2014
Proceedings of the 2nd Annual Meeting of the Berkeley Linguistics Society (1976), pp.
openaire   +2 more sources

Chapter 4, Exercise 2- Locatives

open access: yes, 1994
: Students learn locatives, combined with inanimate nouns- "to the gas station/school/store.

core  

Remarques sur les phrases possessives, existentielles et locatives

open access: yes, 1974
Lyons John. Remarques sur les phrases possessives, existentielles et locatives. In: Langages, 8ᵉ année, n°34, 1974. La linguistique en Grande-Bretagne dans les années soixante, sous la direction de Jacques Durand et David Robinson. pp.
Lyons, John
core   +1 more source

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