Results 71 to 80 of about 1,122 (295)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Clitics: Lexicalization Patterns of the So-called 3rd Person Dative
Catalan Journal of Linguistics, 2002 Manzini and Savoia (1999, 2001, 2002, to appear) argue that the basic facts about the clitic string are best accounted for without having recourse to anything but a minimalist syntactic compo- nent, i.e.
Rita Manzini, Leonardo M. Savoia
doaj +1 more source
A Typology of Locatives and Event Composition in English
, 2000 This paper, based on Nam's (1995) logic of space, proposes a compositional semantics of event structures in terms of eventuality type of predicates and the semantics of locatives.
Nam, Seungho
core
, 2004 The article deals with the system of four postpositional locatives and synonymous prepositional constructions. The system of four postpositional locatives in Daukša's "Postilla" is quite well represented. The Polish prepositional constructions of Wujek's
Žilinskaitė, Eglė, +1 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The syntax of existential sentences in Serbian
, 2008 Freeze (1992) argued on the basis of data from several different languages that there is a close relationship between existential sentences (stating the existence of an entity) and locative sentences (stating the location of an entity).
Milicevic, Nataša, Hartmann, Jutta M.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Alain Peyraube : Les constructions locatives en chinois moderne
, 1980 Paris Marie-Claude. Alain Peyraube : Les constructions locatives en chinois moderne. In: Cahiers de linguistique - Asie orientale, vol. 8, 1980. pp.
Paris, Marie-Claude
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source