Results 41 to 50 of about 276,614 (300)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Development and Evaluation of a Tutorial to Improve Students' Understanding of a Lock-in amplifier

open access: yes, 2016
A lock-in amplifier is a versatile instrument frequently used in physics research. However, many students struggle with the basic operating principles of a lock-in amplifier which can lead to a variety of difficulties. To improve students' understanding,
DeVore, Seth   +3 more
core   +2 more sources

A basic lock-in amplifier experiment for the undergraduate laboratory [PDF]

open access: yes, 2003
We describe a basic experiment for the undergraduate laboratory that demonstrates aspects of both, the science and the art of precision electronic measurements. The essence of the experiment is to measure the resistance of a small length of brass-wire to
Black, E. D.   +2 more
core   +1 more source

USING OF ACTIV THERMOGRAPHY AND LOCK-IN METHOD WITH ULTRASOUND EXICATION FOR DETECTION OF MATERIAL DEFECTS [PDF]

open access: yesScientific Journal of Silesian University of Technology. Series Transport, 2014
The main purpose of paper is presented an innovative approach in the field of infrared thermal imaging and its integration into the area of engineering applications.
Milan SAPIETA   +2 more
doaj  

Understanding the Influence of Wake Cavitation on the Dynamic Response of Hydraulic Profiles under Lock-In Conditions

open access: yesEnergies, 2021
To accelerate the integration of fluctuating renewable energy technologies in the power systems, it is necessary to increase the flexibility of hydropower by operating turbines at off-design conditions.
Rafel Roig   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Kényszerpályák a hazai nagyvárosok fejlesztési stratégiáiban

open access: yesTér és Társadalom
A városi fenntarthatósággal kapcsolatos tudományos diskurzus több évtizedre nyúlik vissza, melyet a jelenkori városkutatások egy erősen interdiszciplináris mederben folytatnak mind a hazai, mind a nemzetközi tudományos térben.
Attila Buzási   +1 more
doaj   +1 more source

Transitional Characteristics of Phase Shift in Lock-in Phenomena of an Oscillating Cylinder

open access: yesJournal of Fluid Science and Technology, 2009
In this study, characteristics of phase lag between displacement of forcibly oscillating test body and velocity fluctuation caused by vortex formation behind the test body were investigated.
Hiroyuki HANIU   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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