Results 51 to 60 of about 283,894 (302)
Journal of Fluid Science and Technology, 2017 This study examines experimentally the vortex-induced vibration (VIV) of a mechanical system with two eigenmodes. A previous experiment setup was refined to enable the experiment, and was placed in a circulating water channel to submerge a movable ...
Yoshiki NISHI, Komei SAITOH
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FluidsThis paper presents a numerical investigation into the vortex-induced vibrations (VIV) of a smooth and a marine-fouled circular cylinder with two degrees of freedom (2DOF), subjected to a turbulent oscillatory flow.
Henry Francis Annapeh +1 more
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Infrared Lock-in Thermography Tests with Optical Feedback
U.Porto Journal of Engineering, 2022 Thermography using a period light stimulation. However, the results are highly dependent on the accuracy of the stimulation source and its dynamic response.
António José Ramos Silva +3 more
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Multi-frequency vortex-induced vibrations of a long tensioned beam in linear and exponential shear flows [PDF]
, 2013 The multi-frequency vortex-induced vibrations of a cylindrical tensioned beam of aspect ratio 200, free to move in the in-line and cross-flow directions within first a linearly and then an exponentially sheared current are investigated by means of direct
Bourguet, Rémi +2 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Pulses for Sustainability: Breaking Agriculture and Food Sectors Out of Lock-In
Frontiers in Sustainable Food Systems, 2018 Crop diversification can improve the sustainability of Western agriculture. In particular, pulses are crops that can help both agriculture and the food industry become more ecological, as they reduce greenhouse gas emissions and help reduce animal-based ...
Marie-Benoit Magrini +8 more
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Disrupting the status quo: a sustainability transitions analysis of the fashion system
Sustainability: Science, Practice, & Policy, 2022 The fashion industry has developed into a complex global system with persistent social and environmental sustainability challenges. Private, public, and civil society actors have condemned these persistent problems and called for system change toward ...
Sophie Buchel +3 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
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