Results 41 to 50 of about 283,894 (302)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Fenntarthatóság és klímaadaptáció a városfejlesztésben – lock-in elemzés Budapest XVII. kerületének példáján keresztül

Tér és Társadalom, 2021
A klímaváltozás hatásai jelentősen befolyásolják a törekvést a fenntarthatóság irányába. A városkutatási témák között az utóbbi években a fenntartható fejlődés fogalma és célrendszere mellett előtérbe került a klímaadaptáció, azaz a klímaváltozáshoz ...
Buzási Attila, Csizovszky Anna
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

USING OF ACTIV THERMOGRAPHY AND LOCK-IN METHOD WITH ULTRASOUND EXICATION FOR DETECTION OF MATERIAL DEFECTS [PDF]

Scientific Journal of Silesian University of Technology. Series Transport, 2014
The main purpose of paper is presented an innovative approach in the field of infrared thermal imaging and its integration into the area of engineering applications.
Milan SAPIETA, Vladimír DEKÝŠ, Peter PASTOREK   +2 more
doaj  

Understanding the Influence of Wake Cavitation on the Dynamic Response of Hydraulic Profiles under Lock-In Conditions

Energies, 2021
To accelerate the integration of fluctuating renewable energy technologies in the power systems, it is necessary to increase the flexibility of hydropower by operating turbines at off-design conditions.
Rafel Roig, Jian Chen, Oscar de la Torre, Xavier Escaler   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Kényszerpályák a hazai nagyvárosok fejlesztési stratégiáiban

Tér és Társadalom
A városi fenntarthatósággal kapcsolatos tudományos diskurzus több évtizedre nyúlik vissza, melyet a jelenkori városkutatások egy erősen interdiszciplináris mederben folytatnak mind a hazai, mind a nemzetközi tudományos térben.
Attila Buzási, Bettina Szimonetta Beszedics-Jäger   +1 more
doaj   +1 more source

Transitional Characteristics of Phase Shift in Lock-in Phenomena of an Oscillating Cylinder

Journal of Fluid Science and Technology, 2009
In this study, characteristics of phase lag between displacement of forcibly oscillating test body and velocity fluctuation caused by vortex formation behind the test body were investigated.
Hiroyuki HANIU, Sangil KIM, Katsumi MIYAKOSHI, Kazunori TAKAI, Mohammad Rofiqul ISLAM   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

On Flickering, Tipping Points, Trajectories, Transitions, Transformations, Regime Shifts, and Resiliences in Tourism: Why Resilient Does Not Mean Better and Why Change is Not Always Sustainable

Via@
The concepts of transition, transformation, tipping points, and resilience have gained currency in recent years given the impacts of crisis events on tourism.
C. Michael Hall
doaj   +1 more source