Results 71 to 80 of about 283,894 (302)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Agriculture biologique et verrouillage des systèmes de connaissances Conventionalisation des filières agroalimentaire bio

open access: yesDesenvolvimento e Meio Ambiente, 2012
La question de la co-existence entre deux systèmes bio, l’un porté par les acteurs historiques, l’autre par les nouveaux acteurs agroindustriels, selon un modèle de bifurcation, est traitée à travers l’hypothèse de conventionalisation.
Pierre Marie Stassart, Daniel Jamar
doaj   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu   +5 more
wiley   +1 more source

Climate geoengineering: issues of path-dependence and socio-technical lock-in [PDF]

open access: yes, 2014
As academic and policy interest in climate geoengineering grows, the potential irreversibility of technological developments in this domain has been raised as a pressing concern.
Arthur   +90 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu   +10 more
wiley   +1 more source

Inefficient Lock-in and Subsidy Competition [PDF]

open access: yes
This paper shows that subsidy competition may be efficiency enhancing. We model a subsidy game among two asymmetric regions in a new trade model, where capital can freely move among regions, but capital rewards are repatriated.
Hyun-Ju Koh   +2 more
core   +3 more sources

Community-Based Virtual Power Plants: Against All Odds?

open access: yesProceedings, 2019
Based on a European project entitled “Community-based Virtual Power Plants’ (Interreg 2017–2010) this paper discusses opportunities for community energy projects—focusing on the example of community-based virtual power plants.
Ruth Mourik   +3 more
doaj   +1 more source

Shareholder Lock-In Contracts: Share Price and Trading Volume Effects at the Lock-In Expiry [PDF]

open access: yes
This paper unveils the diversity in lock-in agreements of firms listed on the Nouveau Marche stock exchange in France.We give the main economic reasons why shareholders adopt lock-in agreements that are more stringent than legally required.We relate the ...
Angenandt, P.P.   +2 more
core   +1 more source

Lock-in detection for pulsed electrically detected magnetic resonance [PDF]

open access: yes, 2011
We show that in pulsed electrically detected magnetic resonance (pEDMR) signal modulation in combination with a lock-in detection scheme can reduce the low-frequency noise level by one order of magnitude and in addition removes the microwave-induced non ...
Alexander Schnegg   +12 more
core   +2 more sources

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai   +5 more
wiley   +1 more source

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