Results 141 to 150 of about 2,106,842 (293)

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

open access: yesAdvanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang   +7 more
wiley   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li   +8 more
wiley   +1 more source

Disorder Driven Anisotropic Nonlinear Hall Effect in the Kagome Metal YbCo6Ge6 at Room Temperature

open access: yesAdvanced Science, EarlyView.
The intrinsic structural disorder and short‐range correlated motifs in the kagome metal YbCo6Ge6 constitute the primary mechanism for a robust and anisotropic nonlinear Hall effect (NLHE). This effect is sustained across a wide temperature range, achieving a nonlinear responsivity of up to ∼4.5 × 10−3 m/V at 70 K, higher than known disordered and ...
Qurat Ul Ain   +11 more
wiley   +1 more source

Abstract Representation of Movement Parameters in Basal Ganglia Output

open access: yesAdvanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero   +3 more
wiley   +1 more source

Passive Metasurface Tweezers for Multi‐Scale Orbital Transport and Trapping on Elastic Plates

open access: yesAdvanced Science, EarlyView.
Passive labyrinthine phase encoding converts single‐channel excitation into localized flexural‐wave vortices with programmable orbital angular momentum. The resulting vortex fields enable cross‐scale particle manipulation, including orbital transport, central confinement, and rotational actuation.
Zeyang Bi   +7 more
wiley   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

open access: yesAdvanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu   +11 more
wiley   +1 more source

Passive mode locking of a diode-end-pumped Nd : GdVO4 laser with a semiconductor saturable absorber mirror

open access: yes, 2003
We report an end-pumped and passive mode-locking all-solid-state laser. The laser consists of a Nd:GdVO4 crystal and a linear resonator with a semiconductor saturable absorber mirror that yield mode locking.
Li G   +5 more
core  

Bioinspired Metastable Transient Peeling for Repeatable Rapid Release

open access: yesAdvanced Science, EarlyView.
Inspired by the explosive seed ejection of the squirting cucumber, this work introduces metastable transient peeling that temporally regulates stored interfacial energy release via a tunable energy barrier. A viscoelastic hemispherical gripper achieves 52 ms ultrafast, residue‐free release with 300 000‐cycle durability, enabling damage‐free handling of
Lvzhou Li   +8 more
wiley   +1 more source

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

open access: yesAdvanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu   +10 more
wiley   +1 more source

Functional MXene Inks for Printed Electronics: Chemistry, Rheology, and Devices

open access: yesAdvanced Science, EarlyView.
Functional MXene inks are emerging as building blocks for MXetronics, connecting MXene synthesis, surface functionalization, ink formulation, and advanced printing with device‐level applications. This review maps how composition, stability, rheology, and processability govern printed structures and enable high‐performance sensors, energy‐storage ...
Shahzaib Ali   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy