Patent for locking mechanism, particulalry used in locking liquid dispensing ...
Bradley, Richard C.
core
Orthogonal Light‐ and Enzyme‐Triggered and‐Gate Prodrugs for Senolytic Therapy
An orthogonal AND‐gate prodrug platform combines 390 nm near‐UV photocleavage with SA‐β‐gal activation to control payload release in senescent cells. Its modular architecture enables 4‐MU fluorescence, doxorubicin‐mediated cytotoxicity, and ARV‐771‐driven BRD4 degradation, supporting stimulus‐controlled senolytic design in cellular and organoid models.
Mengyang Chang +12 more
wiley +1 more source
The "Sandwich" technique using a lateral locking plate and intramedullary reconstruction plate with bone cement for osteoporotic proximal humerus fractures: a case series. [PDF]
Wang Y +5 more
europepmc +1 more source
Effective-Depth-Managed Fusion for Authorized Verification of Topologically Locked Quantum Memory
Authorized verification of quantum information provides a stringent setting for quantum machine learning because the useful label can be coherently present while remaining absent from ordinary classical measurement samples. This work introduces a security-anchor-inspired benchmark family for verifying topologically locked quantum memory.
openaire +2 more sources
An assembly porous titanium/β‐TCP implant is developed to establish a spatially programmable osteogenic microenvironment for enhanced osseointegration. By decoupling mechanical support from bioactive ion release, localized ionic gradients generated from the β‐TCP module direct osteogenic activity and bone ingrowth toward the porous titanium framework ...
Heng Zhang +5 more
wiley +1 more source
Recent Advances in Two-Dimensional Metallic MXenes as High-Performance Saturable Absorbers. [PDF]
Xiong X +5 more
europepmc +1 more source
Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou +3 more
wiley +1 more source
Ti<sub>2</sub>O-Based Saturable Absorbers: From Material Synthesis to Broadband Mode-Locked Fiber Laser Applications. [PDF]
Dai G +6 more
europepmc +1 more source
Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang +15 more
wiley +1 more source
Strain accumulation associated with locked subduction megathrusts revealed by deep-ocean borehole observations. [PDF]
Sun T, Davis EE.
europepmc +1 more source

