Results 201 to 210 of about 742,295 (257)

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

Intramedullary cement augmentation in locking plate fixation for Neer four-part proximal humeral fractures: a technique for preventing early mechanical failure. [PDF]

J Orthop Surg Res
Chen Z, Hao C, Cui B, Wu L, Wang C, Zhang Z, Han S.   +6 more
europepmc   +1 more source

NS1‐Induced PARP1 Phase Transitions Prolongs Host Transcriptional Pausing to Promote Influenza A Virus Replication

Advanced Science, EarlyView.
After IAV infection, NS1 induces PARP1 phase transition, reducing molecular mobility in condensates, prolonging host transcriptional pause, aiding RdRp cap snatching, and promoting viral transcription. ABSTRACT Influenza A virus (IAV) commandeers host transcriptional machinery to replicate, but mechanisms remain elusive.
Shufeng Ma, Changyuan Kang, Xixian Liu, Lichao Yang, Mengyi Li, Yuting Ye, Jianfang Zhang, Yingjun Li, Guanghui Jin, Yang Liu, Xiaohong Chen, Kexin Wang, Zifeng Yang   +12 more
wiley   +1 more source

Comparison of the mechanical performance of intramedullary nail and locking plate in tibiotalocalcaneal arthrodesis : a finite element analysis. [PDF]

Bone Joint Res
Zhang H, Mangwani J, Wei F, Song Q, Ling SK, Fong DTP, Li S.   +6 more
europepmc   +1 more source

Customized Itinerant Frequency Combs by Cascaded Nonlinear Effects

Advanced Science, EarlyView.
A cascaded third‐order nonlinear system generates an itinerant frequency comb with the comb center frequency decoupled from the cavity resonance. This enables arbitrary spectral scaling, flexible spacing adjustments, and real‐time central‐frequency engineering, allowing comb splicing and subdivision. The resulting versatility and reconfigurability open
Yi Wang, Yulong Liu, Zeji Li, Wenyan Wang, Sihan Wang, Cheng Wang, Jingwei Zhou, Jie‐Qiao Liao, Tiefu Li   +8 more
wiley   +1 more source

Preoperative-to-Postoperative Radiological Outcomes Following Open Reduction and Internal Fixation With Volar Locking Plate in Adult Distal Radius Fractures: A Prospective Observational Study. [PDF]

Cureus
Singh AK, Bhoumik ID, Choudhary A.
europepmc   +1 more source

Shear‐Mode Direct Piezoelectric Response of Ferroelectric Nematic Liquid Crystals

Advanced Science, EarlyView.
Periodic shear‐induced electric current measurements are reported on two archetypic ferroelectric nematic liquid crystal compounds. From the temperature, frequency and shear angle dependent results of the first and second harmonic current signals together with temperature and oscillatory rheology measurements, the effective piezoelectric coupling ...
Péter Salamon, Marcell Tibor Máthé, Hiroya Nishikawa, Fumito Araoka, Antal Jákli   +4 more
wiley   +1 more source

Biomechanical and clinical comparison of a novel dual-wing locking plate versus the PHILOS plate for neer three- and four-part proximal humeral fractures: a finite element analysis combined with a retrospective cohort study. [PDF]

Front Bioeng Biotechnol
Ji J, Zhao Q, Wei S, Hu X, Deng Y, Chen Z, Gu J, Chen C.   +7 more
europepmc   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Long-term clinical and radiographic outcomes after locking plate fixation of proximal humerus fractures: a 6-year follow-up study. [PDF]

JSES Int
Theopold J, Schöbel T, Youssef Y, Hepp P.   +3 more
europepmc   +1 more source