Results 31 to 40 of about 212,726 (302)

Thermodynamics of Animal Locomotion [PDF]

open access: yesPhysical Review Letters, 2020
Muscles are biological actuators extensively studied in the frame of Hill's classic empirical model as isolated biomechanical entities, which hardly applies to a living organism subjected to physiological and environmental constraints. Here we elucidate the overarching principle of a \emph{living} muscle action for locomotion, considering it from the ...
Herbert, E.   +4 more
openaire   +5 more sources

Horizontal running inside circular walls of Moon settlements: a comprehensive countermeasure for low-gravity deconditioning?

open access: yesRoyal Society Open Science
Long-lasting exposure to low gravity, such as in lunar settlements planned by the ongoing Artemis Program, elicits muscle hypotrophy, bone demineralization, cardio-respiratory and neuro-control deconditioning, against which optimal countermeasures are ...
Alberto E. Minetti   +3 more
doaj   +1 more source

Ecological Burden of Modern Surgery: An Analysis of Total Knee Replacement’s Life Cycle

open access: yesArthroplasty Today, 2023
Background: It is estimated that surgical procedures account for 20%-30% of the greenhouse gases emissions from health-care systems. Total knee replacements (TKR) are one of the most frequently performed procedures in orthopaedics.
Camille Delaie, MD   +7 more
doaj   +1 more source

Sitting for Too Long, Moving Too Little: Regular Muscle Contractions Can Reduce Muscle Stiffness During Prolonged Periods of Chair-Sitting

open access: yesFrontiers in Sports and Active Living, 2021
In modern Western societies, sedentary behavior has become a growing health concern. There is increasing evidence that prolonged sitting periods can be associated with musculoskeletal disorders.
Alexander R. Kett   +3 more
doaj   +1 more source

Wet adhesion and adhesive locomotion of snails on anti-adhesive non-wetting surfaces [PDF]

open access: yes, 2012
Creating surfaces capable of resisting liquid-mediated adhesion is extremely difficult due to the strong capillary forces that exist between surfaces.
McHale Glen   +14 more
core   +2 more sources

Investigation of Eye Movements during Walking in Real and Simulated Environments [PDF]

open access: yes, 2012
This thesis reports experimental research on locomotion simulators, improving design methods and investigating human performance in simulator environments (SE) in comparison with real-world environments (RE).
Zhao, Ming
core   +5 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Locomotive Fireboxes [PDF]

open access: yesJournal of the Institution of Locomotive Engineers, 1917
n ...
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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