Results 51 to 60 of about 212,726 (302)
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Purpose Large correction in opening wedge high tibial osteotomy (HTO) may lead to excessive joint line obliquity (JLO). This study hypothesized that the presence of an oblique joint line, defined by knee joint line obliquity (KJLO) > 5° and/or medial ...
Lilia Gharbi +7 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Brachiation robots mimic the locomotion of bio-primates, including continuous brachiation and ricochetal brachiation. The hand-eye coordination involved in ricochetal brachiation is complex.
Chi-Ying Lin, Jhe-Ming Lee
core +1 more source
While walking, ground reaction forces point from the centre of pressure to the neighbourhood of a focal point, namely the virtual pivot point (VPP), that adjusts angular momentum around the centre of mass (CoM).
Vahid Firouzi +4 more
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
The Balancing of Locomotives [PDF]
n ...
openaire +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
LOCOMOTION-h2020/WILIAM_model_VENSIM: WILIAM_v1.3
<p>Last LOCOMOTION WILIAM release for public use.
Products derived from LOCOMOTION h2020
core +1 more source

