Results 51 to 60 of about 212,726 (302)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Lack of evidence for an effect of joint line obliquity after medial opening wedge high tibial osteotomy: A 12‐year single‐centre retrospective study

open access: yesJournal of Experimental Orthopaedics
Purpose Large correction in opening wedge high tibial osteotomy (HTO) may lead to excessive joint line obliquity (JLO). This study hypothesized that the presence of an oblique joint line, defined by knee joint line obliquity (KJLO) > 5° and/or medial ...
Lilia Gharbi   +7 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Multi-Locomotion Design and Implementation of Transverse Ledge Brachiation Robot Inspired by Sport Climbing

open access: yes, 2023
Brachiation robots mimic the locomotion of bio-primates, including continuous brachiation and ricochetal brachiation. The hand-eye coordination involved in ricochetal brachiation is complex.
Chi-Ying Lin, Jhe-Ming Lee
core   +1 more source

Exploring the control of whole-body angular momentum in young and elderly based on the virtual pivot point concept

open access: yesRoyal Society Open Science
While walking, ground reaction forces point from the centre of pressure to the neighbourhood of a focal point, namely the virtual pivot point (VPP), that adjusts angular momentum around the centre of mass (CoM).
Vahid Firouzi   +4 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Articulated Locomotives [PDF]

open access: yesJournal of the Institution of Locomotive Engineers, 1920
n ...
openaire   +2 more sources

The Balancing of Locomotives [PDF]

open access: yesProceedings of the Institution of Mechanical Engineers, 1901
n ...
openaire   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

LOCOMOTION-h2020/WILIAM_model_VENSIM: WILIAM_v1.3

open access: yes
<p>Last LOCOMOTION WILIAM release for public use.
Products derived from LOCOMOTION h2020
core   +1 more source

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