Results 71 to 80 of about 212,726 (302)

Central Pattern Generator (CPG)-Based Locomotion Control and Hydrodynamic Experiments of Synergistical Interaction between Pectoral Fins and Caudal Fin for Boxfish-like Robot

open access: yes, 2023
Locomotion control of synergistical interaction between fins has been one of the key problems in the field of robotic fish research owing to its contribution to improving and enhancing swimming performance.
Lin Chen, Yueri Cai, Shusheng Bi
core   +1 more source

Autograft Augmentation of Patellar Tendon Rupture Allows Better Functional Outcomes and Less Reoperation Than Steel Wire Cerclage

open access: yesOrthopaedic Journal of Sports Medicine
Background: Patellar tendon rupture is uncommon but can severely impair knee extension and functional recovery. Most injuries occur during sports involving eccentric quadriceps loading, often with valgus stress.
Paul Sempere MD   +6 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Neuromechanical force-based control of a powered prosthetic foot

open access: yesWearable Technologies, 2020
This article presents a novel neuromechanical force-based control strategy called FMCA (force modulated compliant ankle), to control a powered prosthetic foot.
Amirreza Naseri   +3 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

ON LOCOMOTIVE ENGINES. [PDF]

open access: yesMinutes of the Proceedings of the Institution of Civil Engineers
n ...
openaire   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Short‐term patient‐reported outcomes following rectus femoris versus quadriceps tendon and hamstring tendon autografts for ACL reconstruction with concomitant anterolateral procedure: A prospective comparative study

open access: yesJournal of Experimental Orthopaedics
Purpose To compare short‐term patient‐reported outcomes following anterior cruciate ligament reconstruction (ACLR) with concomitant anterolateral procedure, using rectus femoris (RF), quadriceps tendon (QT) and hamstring tendons (HS) autografts.
Tomas Pineda   +5 more
doaj   +1 more source

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