Results 31 to 40 of about 3,874,852 (249)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Lameness changes the behavior of dairy cows: daily rank order of lying and feeding behavior decreases with increasing number of lameness indicators present in cow locomotion [PDF]

, 2022
Lameness is a major animal welfare problem in modern dairy farms. Although association between cow behavior and lameness is proven, functioning and reliable on-farm applications for automatic lameness detection is still lacking because large within and ...
Frondelius, Lilli, Pastell, Matti, Lindeberg, Heli   +2 more
core   +1 more source

Decoding locomotion from population neural activity in moving C. elegans

eLife, 2021
We investigated the neural representation of locomotion in the nematode C. elegans by recording population calcium activity during movement. We report that population activity more accurately decodes locomotion than any single neuron.
Kelsey M Hallinen, Ross Dempsey, Monika Scholz, Xinwei Yu, Ashley Linder, Francesco Randi, Anuj K Sharma, Joshua W Shaevitz, Andrew M Leifer   +8 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Hunting by the Stroke: How Foraging Drives Diving Behavior and Locomotion of East-Greenland Narwhals (Monodon monoceros)

Frontiers in Marine Science, 2021
Deep diving air-breathing species by necessity must balance submergence time and level of exercise during breath-holding: a low activity level preserves oxygen stores and allows longer duration submergence whereas high activity levels consume oxygen ...
Outi M. Tervo, Susanne Ditlevsen, Manh C. Ngô, Nynne H. Nielsen, Susanna B. Blackwell, Terrie M. Williams, Mads Peter Heide-Jørgensen   +6 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

A GABAergic Maf-expressing interneuron subset regulates the speed of locomotion in Drosophila

Nature Communications, 2019
Spinal interneurons (IN) coordinate motoneuron activity to modulate locomotion behavior. Here, the authors characterize a subset of IN subtypes expressing the Maf transcription factor Traffic Jam (TJ) and report the distinct effects of their activation ...
H. Babski, T. Jovanic, C. Surel, S. Yoshikawa, M. F Zwart, J. Valmier, J. B. Thomas, J. Enriquez, P. Carroll, A. Garcès   +9 more
doaj   +1 more source

Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding

Frontiers in Endocrinology, 2021
Leptin is an anorexigenic hormone, important in the regulation of body weight. Leptin plays a role in food reward, feeding, locomotion and anxiety. Leptin receptors (LepR) are expressed in many brain areas, including the midbrain.
Véronne A. J. de Vrind, Lisanne J. van ‘t Sant, Annemieke Rozeboom, Mieneke C. M. Luijendijk-Berg, Azar Omrani, Roger A. H. Adan, Roger A. H. Adan   +6 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Cocaine modulates locomotion behavior in C. elegans.

PLoS ONE, 2009
Cocaine, a potent addictive substance, is an inhibitor of monoamine transporters, including DAT (dopamine transporter), SERT (serotonin transporter) and NET (norepinephrine transporter).
Alex Ward, Vyvyca J Walker, Zhaoyang Feng, X Z Shawn Xu   +3 more
doaj   +1 more source