Results 1 to 10 of about 625,503 (119)

Predicting Parallelism and Quantifying Divergence in Microbial Evolution Experiments

mSphere, 2022
The degree to which independent populations subjected to identical environmental conditions evolve in similar ways is a fundamental question in evolution.
William R. Shoemaker, Jay T. Lennon
doaj   +1 more source

Prevalent emergence of reciprocity among cross-feeding bacteria

ISME Communications, 2022
Explaining the de novo evolution of obligate cooperative cross-feeding interactions among bacteria is a fundamental problem. A critical step during this process is the emergence of reciprocity among two interaction partners, because a mutually beneficial
Samir Giri, Ghada Yousif, Shraddha Shitut, Leonardo Oña, Christian Kost   +4 more
doaj   +1 more source

Using flow cytometry for mitochondrial assays

MethodsX, 2020
The understanding of how different cell types adapt their metabolism in the face of challenges has been attracting the attention of researchers for many years. Recently, immunologists also started to focus on how the metabolism of immune cells can impact
Lauar de Brito Monteiro, Gustavo Gastão Davanzo, Cristhiane Favero de Aguiar, Pedro M.M. Moraes-Vieira   +3 more
doaj   +1 more source

Unlocking the potential of experimental evolution to study drug resistance in pathogenic fungi. [PDF]

NPJ Antimicrob Resist
Jacobs S, Boccarella G, van den Berg P, Van Dijck P, Carolus H.   +4 more
europepmc   +2 more sources

Genetic Polymorphism Drives Susceptibility Between Bacteria and Bacteriophages

Frontiers in Microbiology, 2021
Phage therapy has attracted much attention for the treatment of antibiotic-resistant bacteria in recent years. However, it is common for bacteria to obtain resistance capability in short time after interaction with a lytic phage, as observed in phage ...
Xiaoxu Zhang, Xiaoxu Zhang, Dongyan Xiong, Dongyan Xiong, Junping Yu, Hang Yang, Ping He, Ping He, Hongping Wei   +8 more
doaj   +1 more source

Bacterial evolution on demand

eLife, 2021
Bacteria carry antibiotic resistant genes on movable sections of DNA that allow them to select the relevant genes on demand.
Pål J Johnsen, João A Gama, Klaus Harms   +2 more
doaj   +1 more source

Escherichia coli with a Tunable Point Mutation Rate for Evolution Experiments

G3: Genes, Genomes, Genetics, 2020
The mutation rate and mutations’ effects on fitness are crucial to evolution. Mutation rates are under selection due to linkage between mutation rate modifiers and mutations’ effects on fitness.
Nicholas A. Sherer, Thomas E. Kuhlman
doaj   +1 more source

A novel decoy strategy for polymyxin resistance in Acinetobacter baumannii

eLife, 2021
Modification of the outer membrane charge by a polymyxin B (PMB)-induced PmrAB two-component system appears to be a dominant phenomenon in PMB-resistant Acinetobacter baumannii.
Jaeeun Park, Misung Kim, Bora Shin, Mingyeong Kang, Jihye Yang, Tae Kwon Lee, Woojun Park   +6 more
doaj   +1 more source

Failure to progress

eLife, 2021
Experiments on yeast cells that are hosts to a killer virus confirm that natural selection can sometimes reduce fitness.
Duncan Greig, Jasmine Ono
doaj   +1 more source

A Novel Small RNA on the Pseudomonas putida KT2440 Chromosome Is Involved in the Fitness Cost Imposed by IncP-1 Plasmid RP4

Frontiers in Microbiology, 2020
Plasmids can provide advantageous traits to host bacteria, although they may impose a fitness cost. Chromosome-encoded factors are important for regulating the expression of genes on plasmids, and host chromosomes may differ in terms of their ...
Hibiki Kawano, Chiho Suzuki-Minakuchi, Chiho Suzuki-Minakuchi, Daisuke Sugiyama, Natsuki Watanabe, Yurika Takahashi, Kazunori Okada, Hideaki Nojiri, Hideaki Nojiri   +8 more
doaj   +1 more source