Results 41 to 50 of about 751,176 (305)

Genetic variation in adaptability and pleiotropy in budding yeast

eLife, 2017
Evolution can favor organisms that are more adaptable, provided that genetic variation in adaptability exists. Here, we quantify this variation among 230 offspring of a cross between diverged yeast strains.
Elizabeth R Jerison, Sergey Kryazhimskiy, James Kameron Mitchell, Joshua S Bloom, Leonid Kruglyak, Michael M Desai   +5 more
doaj   +1 more source

Adaptation and compensation in a bacterial gene regulatory network evolving under antibiotic selection

eLife, 2021
Gene regulatory networks allow organisms to generate coordinated responses to environmental challenges. In bacteria, regulatory networks are re-wired and re-purposed during evolution, though the relationship between selection pressures and evolutionary ...
Vishwa Patel, Nishad Matange
doaj   +1 more source

Experimental evolution recapitulates natural evolution

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000
Genomes of the closely related bacteriophages ϕX174 and S13 are 5386 bases long and differ at 114 nucleotides, affecting 28 amino acids. Both parental phages were adapted to laboratory culture conditions in replicate lineages and analysed for nucleotide changes that accumulated experimentally.
H A, Wichman, L A, Scott, C D, Yarber, J J, Bull   +3 more
openaire   +3 more sources

The role of calcium and predation on plate morph evolution in the three-spined stickleback (Gasterosteus aculeatus) [PDF]

, 2014
While the genetic basis to plate morph evolution of the three-spined stickleback (Gasterosteus aculeatus) is well described, the environmental variables that select for different plate and spine morphs are incompletely understood.
Przybylski, Miroslaw, Barber, I, C. Smith (2247166), Smith, C, Robert J. Wootton, R. Spence (7654601), Wootton, RJ, Przybylski, M, Spence, R, Mirosław Przybylski, Smith, Carl, Spence, Rowena Grace Alison, Iain Barber (348101), Rowena Spence, Iain Barber, Wootton, Robert, Carl Smith, R. J. Wootton (7654604), Barber, Iain, M. Przybylski (2489125)   +19 more
core   +1 more source

Deep mutational scanning and CRISPR-engineered viruses: tools for evolutionary and functional genomics studies

mSphere
Recent advancements in synthetic biology and sequencing technologies have revolutionized the ability to manipulate viral genomes with unparalleled precision.
Mercedes Paz, Gonzalo Moratorio
doaj   +1 more source

Ecological causes of morphological evolution in the three-spined stickleback [PDF]

, 2013
The central assumption of evolutionary theory is that natural selection drives the adaptation of populations to local environmental conditions, resulting in the evolution of adaptive phenotypes.
C. Smith (2247166), Robert J. Wootton, Wootton, R.J., R. Spence (7654601), Mirosław Przybylski, Smith, Carl, Spence, Rowena Grace Alison, Iain Barber (348101), Rowena Spence, Iain Barber, Przybylski, Mirosław, Carl Smith, R. J. Wootton (7654604), Barber, Iain, M. Przybylski (2489125)   +14 more
core   +1 more source

The Classification and Evolution of Bacterial Cross-Feeding [PDF]

, 2019
Bacterial feeding has evolved toward specific evolutionary niches and the sources of energy differ between species and strains. Although bacteria fundamentally compete for nutrients, the excreted products from one strain may be the preferred energy ...
Shorten PR, McNabb WC, Altermann E, Roy NC, Smith NW   +4 more
core   +5 more sources

R5 HIV‐1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5

EMBO Molecular Medicine, 2013
The gastrointestinal tract is a principal route of entry and site of persistence of human immunodeficiency virus type 1 (HIV‐1). The intestinal mucosa, being rich of cells that are the main target of the virus, represents a primary site of viral ...
Mariangela Cavarelli, Chiara Foglieni, Maria Rescigno, Gabriella Scarlatti   +3 more
doaj   +1 more source

Microbial Experimental Evolution as a Novel Research Approach in the Vibrionaceae and Squid-Vibrio Symbiosis

Frontiers in Microbiology, 2014
The Vibrionaceae are a genetically and metabolically diverse family living in aquatic habitats with a great propensity toward developing interactions with eukaryotic microbial and multicellular hosts (as either commensals, pathogens, and mutualists). The
William eSoto, Michele Kiyoko Nishiguchi
doaj   +1 more source

Experimental models for testing hypotheses about cumulative cultural evolution [PDF]

, 2008
The rapid appearance (over evolutionary time) of the cognitive skills and complex inventions of modern humans has been attributed to “cumulative cultural evolution” (henceforth CCE), the accumulation of knowledge and skills over generations.
Caldwell, C., Millen, Ailsa E., Ailsa E. Millen, Millen, Ailsa, Caldwell, Christine Anna, Christine A. Caldwell   +5 more
core   +1 more source