Results 51 to 60 of about 8,228,186 (254)

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

Cine experimental. Número 1 [PDF]

open access: yes, 1944
Cine experimental (1944). Cine experimental. Número 1.
Cine experimental
core  

Recurrent copy number variations in the human fungal pathogen Candida parapsilosis

open access: yesmBio, 2023
Candida parapsilosis is an opportunistic fungal pathogen with increasing incidence in hospital settings worldwide; however, we lack a comprehensive understanding of the mechanisms promoting its virulence and drug resistance. Bergin et al.
Anna Selmecki
doaj   +1 more source

Experimental evolution of evolvability

open access: yesScience
Evolvability—the capacity to generate adaptive variation—is a trait that can itself evolve through natural selection. However, the idea that mutation can become biased toward adaptive outcomes remains controversial. In this work, we report the evolution of enhanced evolvability through localized hypermutation in experimental populations of bacteria ...
Michael Barnett   +2 more
openaire   +3 more sources

Experimental evolution of immunological specificity [PDF]

open access: yesProceedings of the National Academy of Sciences, 2019
Memory and specificity are hallmarks of the adaptive immune system. Contrary to prior belief, innate immune systems can also provide forms of immune memory, such as immune priming in invertebrates and trained immunity in vertebrates.
Kevin Ferro   +5 more
openaire   +3 more sources

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager   +8 more
wiley   +1 more source

How much conversation content is actually social: human conversational behaviour revisited

open access: yesLanguage and Cognition
Our study explores aspects of human conversation within the framework of evolutionary psychology, focusing on the proportion of ‘social’ to ‘non-social’ content in casual conversation. Building upon the seminal study by Dunbar et al. (1997, Human Nature,
Anna Szala   +7 more
doaj   +1 more source

The landscape of transcriptional and translational changes over 22 years of bacterial adaptation

open access: yeseLife, 2022
Organisms can adapt to an environment by taking multiple mutational paths. This redundancy at the genetic level, where many mutations have similar phenotypic and fitness effects, can make untangling the molecular mechanisms of complex adaptations ...
John S Favate   +4 more
doaj   +1 more source

Experimental evolution of bet hedging [PDF]

open access: yesNature, 2009
Bet hedging-stochastic switching between phenotypic states-is a canonical example of an evolutionary adaptation that facilitates persistence in the face of fluctuating environmental conditions. Although bet hedging is found in organisms ranging from bacteria to humans, direct evidence for an adaptive origin of this behaviour is lacking.
Beaumont, H.   +4 more
openaire   +4 more sources

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens   +6 more
wiley   +1 more source

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