Results 61 to 70 of about 751,176 (305)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Recurrent copy number variations in the human fungal pathogen Candida parapsilosis

mBio, 2023
Candida parapsilosis is an opportunistic fungal pathogen with increasing incidence in hospital settings worldwide; however, we lack a comprehensive understanding of the mechanisms promoting its virulence and drug resistance. Bergin et al.
Anna Selmecki
doaj   +1 more source

Experimental evolution of evolvability

Science
Evolvability—the capacity to generate adaptive variation—is a trait that can itself evolve through natural selection. However, the idea that mutation can become biased toward adaptive outcomes remains controversial. In this work, we report the evolution of enhanced evolvability through localized hypermutation in experimental populations of bacteria ...
Michael Barnett, Lena Meister, Paul B. Rainey   +2 more
openaire   +3 more sources

Phenotypic plasticity and experimental evolution [PDF]

Journal of Experimental Biology, 2006
SUMMARYNatural or artificial selection that favors higher values of a particular trait within a given population should engender an evolutionary response that increases the mean value of the trait. For this prediction to hold, the phenotypic variance of the trait must be caused in part by additive effects of alleles segregating in the population, and ...
Theodore, Garland, Scott A, Kelly
openaire   +3 more sources

The nature of culture : an eight-grade model for the evolution and expansion of cultural capacities in hominins and other animals [PDF]

, 2015
Tracing the evolution of human culture through time is arguably one of the most controversial and complex scholarly endeavors, and a broad evolutionary analysis of how symbolic, linguistic, and cultural capacities emerged and developed in our species is ...
Collard, Mark, Haidle, Miriam Noël, Conard, N., Tennie, Claudio, Bolus, M., Whiten, A., Haidle, M.N., Nowell, April, Haidle, M., Nowell, A., Lombard, Marlize, Haidle, Miriam, Tennie, C., Collard, M., Tennie, C. ; https://orcid.org/, Bolus, Michael, Whiten, Andrew, Garofoli, D., Garafoli, Duilio, Garofoli, Duilio, Conard, N.J., Conard, Nicholas, Lombard, M.   +22 more
core   +2 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

The landscape of transcriptional and translational changes over 22 years of bacterial adaptation

eLife, 2022
Organisms can adapt to an environment by taking multiple mutational paths. This redundancy at the genetic level, where many mutations have similar phenotypic and fitness effects, can make untangling the molecular mechanisms of complex adaptations ...
John S Favate, Shun Liang, Alexander L Cope, Srujana S Yadavalli, Premal Shah   +4 more
doaj   +1 more source

Toward a mechanistic explanation of phenotypic evolution [PDF]

, 2022
S.5-14Reconciling different underlying ontologies and explanatory contexts has been one of the main challenges and impediments for theory integration in biology.
Stadler, P.F., Prohaska, S.J., Laubichler, M.D.   +2 more
core   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

How much conversation content is actually social: human conversational behaviour revisited

Language and Cognition
Our study explores aspects of human conversation within the framework of evolutionary psychology, focusing on the proportion of ‘social’ to ‘non-social’ content in casual conversation. Building upon the seminal study by Dunbar et al. (1997, Human Nature,
Anna Szala, Sławomir Wacewicz, Marek Placiński, Aleksandra Ewa Poniewierska, Arkadiusz Schmeichel, Michal Mikolaj Stefanczyk, Przemysław Żywiczyński, Robin I.M. Dunbar   +7 more
doaj   +1 more source