Results 81 to 90 of about 8,228,186 (254)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Evolution of Specialists in an Experimental Microcosm [PDF]

Genetics, 2004
Abstract The impact of adaptation on the persistence of a balanced polymorphism was explored using the lactose operon of Escherichia coli as a model system. Competition in chemostats for two substitutable resources, methylgalactoside and lactulose, generates stabilizing frequency-dependent selection when two different naturally isolated ...
Daniel E, Dykhuizen, Antony M, Dean
openaire   +2 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The evolution and population diversity of human-specific segmental duplications [PDF]

, 2017
Segmental duplications contribute to human evolution, adaptation and genomic instability but are often poorly characterized. We investigate the evolution, genetic variation and coding potential of human-specific segmental duplications (HSDs). We identify
Nuttle, Xander, Wilson, Richard K, Nelson, Bradley J, Xander Nuttle, Laura Denman, Nelson, Bradley J., Kenneth Mark, Kelsi Penewit, Huddleston, John, Malig, Maika, Cantsilieris, Stuart, Tina A. Lindsay-Graves, Harshman, Lana, John Huddleston, Penn, Osnat, Stessman, Holly A, Stessman, Holly A. F., Wilson, Richard K., Dennis, Megan Y, Espinoza, Claudia, Dennis, Megan Y., Penewit, Kelsi, Francesca Antonacci, Janke, Nicolette, Stuart Cantsilieris, Baker, Carl, Richard K. Wilson, Holly A. F. Stessman, Carl Baker, Lindsay-Graves, Tina A, Bradley J. Nelson, Maika Malig, Evan E. Eichler, Graves, Tina A, Stessman, Holly AF, Megan Y. Dennis, Archana Raja, Lana Harshman, Eichler, Evan E, Hoekzema, Kendra, Nicolette Janke, Lindsay-graves, Tina A., Claudia Espinoza, Mark, Kenneth, Denman, Laura, Eichler, Evan E., Antonacci, Francesca, Raja, Archana, Osnat Penn, Kendra Hoekzema   +49 more
core   +1 more source

Effect of hosts on competition among clones and evidence of differential selection between pathogenic and saprophytic phases in experimental populations of the wheat pathogen Phaeosphaeria nodorum

BMC Evolutionary Biology, 2011
Background Monoculture, multi-cropping and wider use of highly resistant cultivars have been proposed as mechanisms to explain the elevated rate of evolution of plant pathogens in agricultural ecosystems.
Mascher Fabio, McDonald Bruce A, Sommerhalder Rubik J, Zhan Jiasui   +3 more
doaj   +1 more source

Species dynamics in natural bacterial communities over multiple rounds of propagation

Evolutionary Applications, 2022
Our experimental work illustrates how microbial ecosystems can be shaped by selective pressures over long‐term ecological time scales. Natural microbial ecosystems generally consist of various co‐existing species, where community composition describes ...
Anneloes E. Groenenboom, Joost van denHeuvel, Bas J. Zwaan, Eddy J. Smid, Sijmen E. Schoustra   +4 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Journal of Multivariate Experimental Personality and Clinical Psychology, v.1, no.4 (complete version)

, 1975
The fourth issue of the Journal of Multivariate Experimental Personality and Clinical Psychology edited by G.R. Pierson. Editorial policy board: R.B. Cattell, H.J. Eysenck, J.P. Guilford and P.E.

core   +1 more source

Stress adaptation under in vitro evolution influences survival and metabolic phenotypes of clinical and environmental strains of Vibrio cholerae El-Tor

Microbiology Spectrum
Bacterial adaptation to stress can lead to phenotypic variants with diverse levels of niche competitiveness, pathogenicity, and antimicrobial resistance.
Nana Eghele Adade, Stephen Dela Ahator, Inmaculada García-Romero, Macarena Algarañás, Vincent Appiah, Miguel A. Valvano, Samuel Duodu   +6 more
doaj   +1 more source

Potential for Acanthoscelides obtectus to Adapt to New Hosts Seen in Laboratory Selection Experiments

Insects, 2019
Effective pest management strategies for a targeted pest species must rely on accurate, reliable and reproducible estimates of population dynamics. Importance of such approaches is even more conspicuous when assessing pest’s potential to utilize ...
Uroš Savković, Mirko Đorđević, Biljana Stojković   +2 more
doaj   +1 more source