Results 31 to 40 of about 8,228,186 (254)

Adaptive evolution of nontransitive fitness in yeast

open access: yeseLife, 2020
A common misconception is that evolution is a linear ‘march of progress’, where each organism along a line of descent is more fit than all those that came before it.
Sean W Buskirk   +2 more
doaj   +1 more source

Compensatory adaptation and diversification subsequent to evolutionary rescue in a model adaptive radiation

open access: yesEcology and Evolution, 2021
Biological populations may survive lethal environmental stress through evolutionary rescue. The rescued populations typically suffer a reduction in growth performance and harbor very low genetic diversity compared with their parental populations.
Dong‐Hao Zhou, Quan‐Guo Zhang
doaj   +1 more source

Experimental Evolution: The Rate of Adaptive Evolution [PDF]

open access: yesCurrent Biology, 2010
Next-generation sequencing technology allows the identification of molecular changes that have arisen in the genomes of microorganisms undergoing experimental evolution. This permits the elucidation of the molecular evolutionary dynamics in these populations.
openaire   +2 more sources

Genetic variation in adaptability and pleiotropy in budding yeast

open access: yeseLife, 2017
Evolution can favor organisms that are more adaptable, provided that genetic variation in adaptability exists. Here, we quantify this variation among 230 offspring of a cross between diverged yeast strains.
Elizabeth R Jerison   +5 more
doaj   +1 more source

Experimental evolution recapitulates natural evolution

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000
Genomes of the closely related bacteriophages ϕX174 and S13 are 5386 bases long and differ at 114 nucleotides, affecting 28 amino acids. Both parental phages were adapted to laboratory culture conditions in replicate lineages and analysed for nucleotide changes that accumulated experimentally.
H A, Wichman   +3 more
openaire   +3 more sources

Deep mutational scanning and CRISPR-engineered viruses: tools for evolutionary and functional genomics studies

open access: yesmSphere
Recent advancements in synthetic biology and sequencing technologies have revolutionized the ability to manipulate viral genomes with unparalleled precision.
Mercedes Paz, Gonzalo Moratorio
doaj   +1 more source

Adaptation and compensation in a bacterial gene regulatory network evolving under antibiotic selection

open access: yeseLife, 2021
Gene regulatory networks allow organisms to generate coordinated responses to environmental challenges. In bacteria, regulatory networks are re-wired and re-purposed during evolution, though the relationship between selection pressures and evolutionary ...
Vishwa Patel, Nishad Matange
doaj   +1 more source

Experimental evolution gone wild [PDF]

open access: yesJournal of The Royal Society Interface, 2015
Because of their large population sizes and rapid cell division rates, marine microbes have, or can generate, ample variation to fuel evolution over a few weeks or months, and subsequently have the potential to evolve in response to global change.
Scheinin, M.   +4 more
openaire   +3 more sources

R5 HIV‐1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5

open access: yesEMBO Molecular Medicine, 2013
The gastrointestinal tract is a principal route of entry and site of persistence of human immunodeficiency virus type 1 (HIV‐1). The intestinal mucosa, being rich of cells that are the main target of the virus, represents a primary site of viral ...
Mariangela Cavarelli   +3 more
doaj   +1 more source

Microbial Experimental Evolution as a Novel Research Approach in the Vibrionaceae and Squid-Vibrio Symbiosis

open access: yesFrontiers in Microbiology, 2014
The Vibrionaceae are a genetically and metabolically diverse family living in aquatic habitats with a great propensity toward developing interactions with eukaryotic microbial and multicellular hosts (as either commensals, pathogens, and mutualists). The
William eSoto, Michele Kiyoko Nishiguchi
doaj   +1 more source

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