Results 21 to 30 of about 672,102 (258)

Single Locus Clines [PDF]

open access: yesEvolution, 1997
Bazykin (1969) found the form of a single locus cline arising from viability selection against heterozygotes when two populations, initially fixed for alternative alleles, come into contact in a continuous, one-dimensional habitat. Here I have generalized Bazykin's results for the case of postmating reproductive isolation in the form of fertility ...
openaire   +2 more sources

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris   +24 more
wiley   +1 more source

Preface to Locus Solum [PDF]

open access: yesMathematical Structures in Computer Science, 2001
The theory presented here is a new, radical step in the research program that started with linear logic and aiming at an interactive, resource and space conscious account of reasoning and programming.
openaire   +2 more sources

Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas   +7 more
wiley   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

EDITORIAL

open access: yesGlocalism: Journal of Culture, Politics and Innovation
The United Nations Climate Dictionary states that “climate change is the defining issue of our times”. According to this Dictionary, we are facing a global crisis which “refers to the serious problems that are being caused, or are likely to be caused ...
GLOCALISM
doaj   +1 more source

DNA Barcoding of Red Algae (Rhodophyta) in Ternate Island Sea, North Maluku, Indonesia

open access: yesJurnal Ilmiah Perikanan dan Kelautan, 2023
Ternate Island is located on the North Maluku Sea. The North Maluku Sea region includes the Wallacea area and the world's coral triangle. One of the organisms commonly found in this sea is red algae.
Muhammad Janib Achmad   +6 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi   +7 more
wiley   +1 more source

BRIDGING THE GAP: GLOCAL TENSIONS AND GEOPOLITICAL ORDER

open access: yesGlocalism: Journal of Culture, Politics and Innovation
A critical feature of our interconnected world seems particularly relevant nowadays: the inherent tension between glocal reality and a rigid geopolitical order.
GLOCALISM
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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