Results 31 to 40 of about 1,047,476 (293)

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak, Oded Gilad, Yael Feinstein, Sigal Nakav, Ofer Schiller, Joanne Yacobovich   +5 more
wiley   +1 more source

Locus: 25 anos de história [PDF]

, 2020
Editorial of the volume 26, number 1 (2020) of Locus.Editorial del volumen 26, número 1 (2020) de la revista Locus.Editorial do volume 26, número 1 (2020) da revista ...
Pereira Gonçalves, Leandro
core   +1 more source

A new and versatile method for the successful conversion of AFLP-TM markers into simple single locus markers [PDF]

, 2003
Genetic markers can efficiently be obtained by using amplified fragment length polymorphism (AFLP) fingerprinting because no prior information on DNA sequence is required.
Brugmans, B.W., Eck, H., van, Hulst, R.G.M., van der, Visser, R.G.F., Lindhout, W.H.   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationship between parental locus of control and caries experience in preschool children - cross-sectional survey [PDF]

, 2008
Background: Due to high prevalence and serious impacts, childhood caries represents a public health issue. Behavioural risk factors such as locus of health control have been implicated in the development of the disease; however their association with ...
Hynek Pikhart, Broukal, Z, Lencova, E, Erika Lenčová, Tsakos, G, Zdeněk Broukal, Pikhart, H, Georgios Tsakos   +7 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Genome wide analysis of inbred mouse lines identifies a locus containing Ppar-γ as contributing to enhanced malaria surviva [PDF]

, 2010
The genetic background of a patient determines in part if a person develops a mild form of malaria and recovers, or develops a severe form and dies. We have used a mouse model to detect genes involved in the resistance or susceptibility to Plasmodium ...
Winzeler, E.A., Wiltshire, T., Selina E R Bopp, Waters Andrew P., Andrew P. Waters, Luzader, A., Bopp, S.E.R., Waters, A.P., Steffy Brian M., Henson Kerstin, Winzeler Elizabeth A., Ramachandran, V., Suzuki Oscar, Lindstrom, M., Merle Lindstrom, Lindstrom Merle, Oscar Suzuki, Henson, K., Tim Wiltshire, Suzuki, O., Yingyao Zhou, Janse, C., Selina E. R. Bopp, Elizabeth A Winzeler, Spooner, M., Bopp Selina E. R., Zhou Yingyao, Brian M. Steffy, Kerstin Henson, Zhou, Y.Y., Chris Janse, Steffy, B.M., Janse Chris, Wiltshire Tim, Vandana Ramachandran, Muriel Spooner, Luzader Angelina, Angelina Luzader, Ramachandran Vandana, Spooner Muriel, Elizabeth A. Winzeler, Zhou, Y., Brian M Steffy, Andrew P Waters   +43 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

EDITORIAL

Glocalism: Journal of Culture, Politics and Innovation
The United Nations Climate Dictionary states that “climate change is the defining issue of our times”. According to this Dictionary, we are facing a global crisis which “refers to the serious problems that are being caused, or are likely to be caused ...
GLOCALISM
doaj   +1 more source

DNA Barcoding of Red Algae (Rhodophyta) in Ternate Island Sea, North Maluku, Indonesia

Jurnal Ilmiah Perikanan dan Kelautan, 2023
Ternate Island is located on the North Maluku Sea. The North Maluku Sea region includes the Wallacea area and the world's coral triangle. One of the organisms commonly found in this sea is red algae.
Muhammad Janib Achmad, Nebuchadnezzar Akbar, Firdaut Ismail, Ardan Samman, Beginer Subhan, Rustam E Paembonan, Dondy Arafat   +6 more
doaj   +1 more source