Results 41 to 50 of about 28,056 (329)

Causal Powers and the Necessity of Realization [PDF]

, 2017
Non-reductive physicalists hold that mental properties are realized by physical properties. The realization relation is typically taken to be a metaphysical necessitation relation. Here, I explore how the metaphysical necessitation feature of realization
Baysan, Umut
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Linguistic functions and indirect speech acts in tobacco products health warnings

Research in Language
The study incorporates the theory of linguistic functions (Jakobson 1960) and speech act theory (Austin 1962) to analyse the differences and similarities of the language used to produce health warning signs on tobacco-related products in Polish and ...
Julia Koszmider
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Automatic dictionary and rule-based systems for extracting information from text [PDF]

, 2010
The paper offers a general introduction to the use of meta-information in a text mining perspective. The aim is to build a meta-dictionary as an available linguistic resource useful for different applications.
BOLASCO, Sergio, PAVONE P.
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Lack of service (in Chilean law)

Eunomia, 2020
This paper presents a synthesis of meaning of the phrase «lack of service» in Chilean Administrative Law between 1976 and 2002. In first instance, it is argued that this expression designated the French translation of the locution faute de service done ...
Claudio Antonio Agüero San Juan
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Pragmatic Analysis Of Imperative Sentences In The Songs Of Mr.Big Album [PDF]

, 2013
This research is aimed at describing locution and illocution act derived from imperative utterances and classifying illocutionary act from imperative utterances. In collecting data, the writer uses documentation method by selecting imperative utterance.
, Dra. Dwi Haryanti, M. Hum., , Drs. Sigit Haryanto, M. Hum., Cahyono, Zulkarnain Wisnu   +2 more
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