Results 31 to 40 of about 3,310 (283)

À propos de certaines locutions en français [PDF]

open access: yes, 2011
En s’appuyant sur le corpus des locutions analysées dans Locutions en français de J. Dubois (2004), on examinera ici : - la gamme et les degrés de « figement », qui va de locutions dont tous les composants sont fixes et invariables à des locutions dont ...
Dubois-Charlier, Françoise
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Formation de « bonnes » et de « mauvaises » paroles en français

open access: yesActa Universitatis Lodziensis: Folia Litteraria Romanica
L’article est une présentation des formations complexes contenant les éléments bon, mauvais, bien et mal, aussi bien du point de vue morphologique que sémantique.
Anna Bochnakowa
doaj   +1 more source

Dichos y refranes en dialecto vianés de Laureano Prieto (1951) (ms. RAG-C170/5) [PDF]

open access: yesCadernos de Fraseoloxía Galega, 2010
Edición dun manuscrito inédito que contén 385 fraseoloxismos galegos recollidos en 1951 polo etnógrafo Laureano Prieto nos concellos ourensáns de Viana do Bolo, A Gudiña, Vilariño de Conso e As Frieiras (A Mezquita).
Xesús Ferro Ruibal   +1 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

L’émergence des locutions conjonctives de simultanéité en ancien français

open access: yesSHS Web of Conferences, 2012
Ce travail, consacré à l’étude des locutions conjonctives de simultanéité dans le premier état du français écrit, a pour objet de mettre en perspective leur émergence.
Ben Hamad Leïla
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Problematique de la traduction des metaphores, locutions et expressions toutes faites [PDF]

open access: yesMatn/Pizhūhī-i Adabī, 2001
Le present article a pour obiectif de faire decouvrir d'une part les exigences entourant la traduction des metaphores, locutions, expressions toutes faites, et d'autrc part de montrer les dangers que presente le transcodage de ccrtaincs associations d ...
fatemeh tehrani
doaj   +1 more source

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