Results 181 to 190 of about 57,725 (204)

Detection of Nitazenes in the Illicit Drug Supply Utilizing Precursor Ion Scan Methods With Paper Spray Mass Spectrometry

Drug Testing and Analysis, EarlyView.
Nitazenes are increasingly present in the illicit drug supply, complicating harm reduction efforts. We have developed a rapid, nontargeted precursor ion scan method to detect emerging nitazenes in real‐world opioid samples. The method identified multiple nitazenes, often replacing pharmaceutical opioids or mixed with fentanyl and benzodiazepines ...
Allie Miskulin, Irene Shkolnikov, Jindar Sboto, Collin Kielty, Bruce Wallace, Chris G. Gill, Dennis K. Hore   +6 more
wiley   +1 more source

An Investigation Into the Yields of 3,4‐Methylenedioxyphenyl‐2‐propanone (MDP2P) From Glycidate Pre‐Precursors

Drug Testing and Analysis, EarlyView.
Hydrolysis of the glycidate pre‐precursors MMDMG and EMDMG was evaluated for MDP2P production. Acid hydrolysis of MMDMG (HCl, 100°C, 18 h) yielded the highest MDP2P recovery (79%), whereas base hydrolysis produced only slightly lower yields (73%), demonstrating both pathways are effective routes to this key MDMA precursor.
Alexandra L. Mercieca, Ella S. Schuett, Andrew M. McDonagh, Shanlin Fu, Morgan Alonzo   +4 more
wiley   +1 more source

Population Pharmacokinetics and Detection Times of Betamethasone After Intravenous, Intramuscular, and Intranasal Jet Administration of Betamethasone Sodium Phosphate in Horses

Drug Testing and Analysis, EarlyView.
Betamethasone concentrations in 20 horses from Japan and Germany following IV, IM, and INJ administration of betamethasone phosphate were analyzed using population pharmacokinetic modeling. For IV administration of 0.04 mg/kg q24 h, IPC and IUC were 0.012 and 0.31 ng/mL, respectively; the IUC approximated the IFHA urine ISL (0.20 ng/mL).
Taisuke Kuroda, Marc Machnik, Mario Thevis, Yohei Minamijima, Gary Ngai‐Wa Leung, Motoi Nomura, Fumiaki Mizobe, Yuhiro Ishikawa, Kazuhiro Kamiya, Pierre‐Louis Toutain   +9 more
wiley   +1 more source

Comprehensive Evaluation of Commercial Antibodies for High Sensitivity Detection of EPO‐Doping on Western Blots

Drug Testing and Analysis, EarlyView.
A large‐scale evaluation of 164 commercially available anti‐human EPO antibodies was conducted to identify an alternative to clone AE7A5 anti‐EPO antibody used in doping control for the detection of erythropoiesis‐stimulating agents (ERAs) on Western blots.
Christian Reichel, Günter Gmeiner, Hans Geyer, Mario Thevis   +3 more
wiley   +1 more source

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Research on UT1-UTC and LOD Prediction Algorithm Based on Denoised EAM Dataset

Remote Sensing, 2023
Yuanwei Wu, Xishun Li
exaly  

Lods, wrods, and mods: The interpretation of lod scores calculated under different models

Genetic Epidemiology, 1994
Robert Elston, Susan E Hodge
exaly  

The Power to Detect Linkage in Complex Disease by Means of Simple LOD-Score Analyses

American Journal of Human Genetics, 1998
Susan E Hodge, D A Greenberg
exaly  

Further Evidence for the Increased Power of LOD Scores Compared with Nonparametric Methods

American Journal of Human Genetics, 1999
Veronica Vieland, D A Greenberg, Martina Durner   +2 more
exaly  

Allele-Sharing Models: LOD Scores and Accurate Linkage Tests

American Journal of Human Genetics, 1997
Augustine Kong, Nancy Cox
exaly  

A new hybrid method to improve the ultra-short-term prediction of LOD

Journal of Geodesy, 2020
Harald Schuh, Mostafa Hoseini, Sadegh Modiri   +2 more
exaly