Results 101 to 110 of about 434,695 (312)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Critical Genealogy, Comprehension, and Explanation in Leibniz’s Critique of Bayle on Cosmic Dualism

open access: yesReligions
The main aim of this paper is to provide an account of Leibniz’s engagement with the doctrine of cosmic dualism in his Theodicy, i.e., the view that there are two distinct fundamental principles that are responsible for the existence of the created world,
Paul Lodge
doaj   +1 more source

The Emily Davison Lodge - "Out of the Archives" [PDF]

open access: yes
A series of commissioned artworks (4) made with Olivia Plender in response to materials in the Women's Library, specifically recovering and re-historicising the suffragette as a militant artist and with a particular emphasis on collating existing records
Plender, Olivia, Reeve, Hester
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Children who bully at school [PDF]

open access: yes
Examines children who bully at school, and specifically on the ways in which parenting and family functioning underpin a child\u27s bullying behaviour. Overview School bullying is a serious problem worldwide.
Jodie Lodge
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Phillip DeVito Honors and Awards: Oregon Wine Press [PDF]

open access: yes, 1994
A stalwart of Oregon wine retires from Maitre d\u27 career, the cover story of the August 1994 edition of Oregon Wine Press, spotlighted Phillip DeVito, who was retiring after a long career in the Oregon wine industry.
Hopkins, Rich
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Working with families whose child is bullying: an evidence-based guide for practitioners [PDF]

open access: yes
This guide aims to provide practitioners and other professionals with information on school bullying and ways to work with and support families with a child who is bullying others.
Jodie Lodge
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

The Whalesong [PDF]

open access: yes, 2003
Academic opportunities for summer and fall -- Self-proclaimed Baghdad mayor prepares for office amid skepticism by city residents -- Everyone's an alcoholic according to AUDIT -- Impeach Bush: I don't think so -- Sad loss at Housing Lodge -- Letters to ...

core  

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