Results 71 to 80 of about 66,966 (283)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Validating the contributions of stem and root traits to barley lodging in western Canada

Frontiers in Plant Science
Lodging caused by stem buckling or root anchorage failure results in significant economic losses each year globally due to increased disease load, downgrading of quality, and yield loss.
Michael W. Taylor, Céline A. M. Ferré, Shengjian Ye, Xuan Yang, J. Allan Feurtado, Aaron D. Beattie   +5 more
doaj   +1 more source

Evaluating Rice Varieties for Suitability in a Rice–Fish Co-Culture System Based on Lodging Resistance and Grain Yield

Agronomy, 2023
Rice–fish co-cultures have been practiced for over 2000 years, and they have tremendous potential in terms of increasing food security and economic benefits.
Meijuan Li, Xiangyu Hu, Rui Hu, Kaiming Liang, Xuhua Zhong, Junfeng Pan, Youqiang Fu, Yanzhuo Liu, Xinyu Wang, Qunhuan Ye, Yuanhong Yin   +10 more
doaj   +1 more source

Progress and bottlenecks in the early domestication of the perennial oilseed Silphium integrifolium, a sunflower substitute [PDF]

, 2018
Silflower (Silphium integrifolium Michx.) is in the early stages of domestication as a perennial version of oilseed sunflower, its close relative. Grain crops with deep perennial root systems will provide farmers with new alternatives for managing soil ...
Crews, Timothy E., González Paleo, Luciana, Peterson, Kelsey, Ravetta, Damián Andrés, Turner, Kathryn, Van Tassel, David, Vilela, Alejandra Elena   +6 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Ancient Wheat Species Can Extend Biodiversity of Cultivated Crops [PDF]

, 2011
Wheat genetic resources may be grown in organic farming systems or in less favourable areas for bread wheat species. Characteristics of hulled wheat species (23 varieties of einkorn, emmer wheat, spelt wheat) were studied and evaluated within a two-year ...
Capouchova, Ivana, Konvalina, Petr, Moudry, Jan, Moudry, Jan (Jr.), Stehno, Zdenek   +4 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Lodging resistance of rice plants studied from the perspective of culm mechanical properties, carbon framework, free volume, and chemical composition

Scientific Reports, 2022
In this study, four varieties of rice were cultivated on the same farmland under same conditions and for same duration. However, their lodging resistance was found to be obviously different from each other.
Qing Liu, Chongshan Yin, Xi Li, Chunqing He, Zhi Ding, Xuan Du   +5 more
doaj   +1 more source

Genetic resources of hulled wheat species in Czech organic farming [PDF]

, 2012
As organic farmers are searching for new market and sale opportunities, the organic farming system may grow and process a wider range of species than the conventional farming system.
Capouchova, Ivana, Konvalina, Petr, Stehno, Zdenek   +2 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source