Results 101 to 110 of about 122,769 (286)
The Journal of Pathology, EarlyView.Abstract Lung cancer is the leading cause of global cancer‐related morbidity and mortality, with tobacco smoking as its strongest risk factor. Nuclear factor erythroid 2‐related factor 2 (NRF2) is a redox‐regulated transcription factor frequently dysregulated in non‐small cell lung cancer (NSCLC), leading to aggressive disease and resistance to therapy.
Jouni Härkönen +14 more
wiley +1 more source
Generation and evaluation of a large mutational library from the Escherichia coli mechanosensitive channel of large conductance, MscL - Implications for channel gating and evolutionary design [PDF]
, 2003 Random mutagenesis of the mechanosensitive channel of large conductance (MscL) from Escherichia coli coupled with a high-throughput functional screen has provided new insights into channel structure and function.
Dougherty, Dennis A., Maurer, Joshua A.
core
CAAI Transactions on Intelligence Technology, EarlyView.ABSTRACT Accurately predicting line loss rates is crucial for effective management in distribution networks, particularly for short‐term multihorizon forecasts ranging from 1 hour to 1 week. In this study, we propose attention‐GCN–LSTM, a novel method that integrates graph convolutional networks (GCN), long short‐term memory (LSTM) and a three‐level ...
Jie Liu +4 more
wiley +1 more source
Using ALoFT to determine the impact of putative loss-of-function variants in protein-coding genes
Nature Communications, 2017 Variants causing loss of function (LoF) of human genes have clinical implications. Here, the authors present a method to predict disease-causing potential of LoF variants, ALoFT (annotation of Loss-of-Function Transcripts) and show its application to ...
Suganthi Balasubramanian +8 more
doaj +1 more source
Inflammation and Neutrophil Oxidative Burst in a Family with NFKB1 p.R157X LOF and Sterile Necrotizing Fasciitis [PDF]
, 2023 Wenny Santaniemi +13 more
openalex +1 more source
Residual Life Assessment of Oil‐Immersed Insulating Paper by FTIR Feature Interpretability Evolution
High Voltage, EarlyView.ABSTRACT The ageing of insulating paper escalates the peril of insulation failure in oil‐impregnated‐paper power equipment. Consequently, the real‐time monitoring and non‐destructive assessment of insulating paper condition assume paramount significance.
Guangyi Liu +8 more
wiley +1 more source
Integrative Zoology, EarlyView.Museum specimens provide a rich source of historical DNA, enabling insights into phylogenetic relationships and demographic history of the endangered Koklass Pheasant. Our findings uncovered a previously unrecognized population in Guizhou province and highlighted elevated extinction risk in populations from Anhui province and Southern China, informing ...
Zhiyong Jiang +9 more
wiley +1 more source