Results 151 to 160 of about 34,114 (259)

Recent Advances in Chemosensors Bearing Pyrazole and Imidazole Rings: An Approach Toward the Detection of Metal Ions Based on these Diazoles

Advanced Sensor Research, Volume 5, Issue 10, October 2026.
This contribution analyzes recent articles (2021–2025) on chemosensors containing pyrazole and imidazole rings for detecting metal ions, using distinctive examples. It focuses on the structural design of probes, their coordination behavior, sensing mechanisms, and analytical performance, including selectivity, sensitivity, working wavelength, and ...
Alexander Ladino‐Bejarano, Carlos Cifuentes, Néstor Bravo, Jaime Portilla   +3 more
wiley   +1 more source

Allele frequencies at recessive disease genes are mainly determined by pleiotropic effects in heterozygotes. [PDF]

Genetics
Judd J, Spence JP, Milind N, Kachuri L, Witte JS, Pritchard JK.   +5 more
europepmc   +1 more source

LOF baseball team

Team picture of the LOF baseball team, year ...
Libbey-Owens-Ford Glass Company
core  

CYP2C19 Genotyping to Guide Clopidogrel Prescribing for Neurovascular Indications: A Survey of Institutional Approaches

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 937-942, October 2026.
Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is commonly used for secondary prevention following acute ischemic stroke (AIS) and neurointerventional procedures. However, the efficacy of clopidogrel is reduced in carriers of CYP2C19 no‐function alleles.
Rachael M. Stone, Glenda Hoffecker, April Schultz, Brittney H. Davis, Salma A. Bargal, Amber L. Beitelshees, Nihal El Rouby, Madeline Norris, Kevin J. Rodriguez, Nita Limdi, Larisa H. Cavallari, Craig R. Lee   +11 more
wiley   +1 more source

RHOA Deletion Downregulates CD19 and Promotes Dysfunctional Immune Microenvironments in CAR-T Resistant Large B-cell Lymphomas. [PDF]

Blood Cancer Discov
Newsam AD, Ziccheddu B, Youssfi AA, Venkatarame Gowda Saralamma V, Foos-Russ S, Tsai DE, Sheffield-Veney I, Jeevan A, Manara P, Goretsky YE, Suissa DM, Russo MV, Fattakhov N, Carmona-Berrio D, Campos Gallego N, Coughlin CA, Sondhi AK, Roberts ER, Spiegel JY, Alderuccio JP, Amador C, Bilbao D, Coffey DG, Jain MD, Maura F, Locke FL, Schatz JH.   +26 more
europepmc   +1 more source

A <i>de novo VPS16</i> missense variant blocks autophagic flux and extends DYT-<i>VPS16</i> into infancy. [PDF]

Autophagy Rep
Gonzalez Saez-Diez E, Xue X, Ebrahimi-Fakhari D.   +2 more
europepmc   +1 more source

In‐Situ Construction of Multi‐Scale Heterogeneous Structures in L‐DED IN718 Coatings via WMoTaNb Incorporation for Enhanced Strength‐Toughness Synergy

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT To improve the strength–toughness balance of IN718, and alleviate the brittleness commonly associated with refractory high‐entropy alloys, this study proposes a novel strategy to fabricate defect‐free IN718/WMoTaNb heterogeneous multiprincipal element alloy coatings via laser‐directed energy deposition.
Zhao Wang, Yinghui Zhou, Jian Chen, Rengen Ding, Wenting Shao, Shuaidan Lu, Ke Yang, Hongge Pan   +7 more
wiley   +1 more source

Association Between Diabetes Mellitus and Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) Loss-of-Function Allele Carriage Among Patients Undergoing Coronary Artery Bypass Grafting: A Cross-Sectional Study. [PDF]

Cureus
Bin-Te Shawkat MS, Kabir ASMH, Ahmed I, Reza MM, Hoque Bulbul MR.   +4 more
europepmc   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, Volume 183, Issue 20, Page 6179-6198, October 2026.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

Automated patch clamp data improve variant classification and penetrance stratification for SCN5A-Brugada syndrome. [PDF]

Eur Heart J
O'Neill MJ, Ma JG, Aldridge JL, Solus JF, Harvey GR, Roberson PH, Barc J, Bezzina CR, Roden DM, Walsh R, Vandenberg JI, Glazer AM, Ng CA.   +12 more
europepmc   +1 more source