Results 141 to 150 of about 34,114 (259)
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò +18 more
wiley +1 more source
PP2A and CDK16 antagonistically regulate WIPI2B phosphorylation and neuronal autophagosome biogenesis. [PDF]
Tsong H, Waxham MN, Stavoe AKH.
europepmc +1 more source
Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton +6 more
wiley +1 more source
<i>CACNA1C</i> Genetic Variants Differentially Affect Neuronal Networks Through Divergent Pathways. [PDF]
Wilkinson G +6 more
europepmc +1 more source
ABSTRACT Background Healthcare overuse, including unnecessary diagnostic testing and procedures, contributes to patient harm, increased healthcare costs, and resource waste. The Choosing Wisely initiative aims to reduce low‐value care through evidence‐based recommendations.
Emma Larsson +10 more
wiley +1 more source
Decaying and expanding Erk gradients process memory of skeletal size during zebrafish fin regeneration. [PDF]
Rich A +9 more
europepmc +1 more source
Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus +7 more
wiley +1 more source

