Results 51 to 60 of about 487,122 (264)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Log-linear distance models of homophily in small groups
Methodological Innovations, 2016 This article demonstrates the innovative use of the log-linear distance model in the assessment of homophily in a set of small groups, such as the co-participants in a set of events. It traces the development of the application of the log-linear distance
Peter J Carrington
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
STUDENTS’ MATHEMATICS KNOWLEDGE – THEORY AND EXERCISES
Journal on Efficiency and Responsibility in Education and Science, 2016 This article analyses the tests results evaluating the knowledge of students of basic mathematics courses at the University of Economics and the University of Finance and Administration in Prague. The relationship between the knowledge of definitions and
ULRYCHOVÁ, Eva
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The predictors of treatment adherence among hypertensive patients with cost-free access
Scientific ReportsThe level and predictors of medication adherence have not been given attention among populations for whom the cost of treatment is not a concern, especially in the Ghanaian healthcare setting.
Felix Kwasi Nyande +7 more
doaj +1 more source
FoodsMonascus ruber is an important fungus that causes spoilage in table olives, resulting in the darkening of the brine, the softening of the fruit, increased pH, and apparent mycelial growth.
Leandro Pereira Cappato +5 more
doaj +1 more source
Deformation-Aware Log-Linear Models [PDF]
, 2009 In this paper, we present a novel deformation-aware discriminative model for handwritten digit recognition. Unlike previous approaches our model directly considers image deformations and allows discriminative training of all parameters, including those accounting for non-linear transformations of the image.
Tobias Gass +2 more
openaire +1 more source