Results 41 to 50 of about 356,775 (282)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A new Maxwell-Log logistic distribution and its applications for mortality rate data

open access: yesJournal of Nigerian Society of Physical Sciences
In this research, we extended the Log-Logistic distribution by incorporating it into the Maxwell generalized class, resulting in the Maxwell-Log Logistic (Max-LL ) distribution.
Uthumporn Panitanarak   +4 more
doaj   +1 more source

On the contraction properties of some high-dimensional quasi-posterior distributions [PDF]

open access: yes, 2016
We study the contraction properties of a quasi-posterior distribution $\check\Pi_{n,d}$ obtained by combining a quasi-likelihood function and a sparsity inducing prior distribution on $\rset^d$, as both $n$ (the sample size), and $d$ (the dimension of ...
Atchadé, Yves F.
core  

Grid multi-category response logistic models. [PDF]

open access: yes, 2015
BackgroundMulti-category response models are very important complements to binary logistic models in medical decision-making. Decomposing model construction by aggregating computation developed at different sites is necessary when data cannot be moved ...
Jiang, Wenchao   +5 more
core   +1 more source

The beta log-logistic distribution

open access: yesBrazilian Journal of Probability and Statistics, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Log logistic distribution to model water demand data [PDF]

open access: yesProcedia Engineering, 2015
There had been insufficient studies previously to conclude the suitability of the appropriate probability distribution functions in modelling water demand. The purpose of this study is to find an appropriate probability density function to apply in simulating water demand using real water consumption data.
Surendran, Seevali, Tota-Maharaj, Kiran
openaire   +2 more sources

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

Optimization of Gamma–Power–Log–logistic distribution and its applications in modelling volume of oil spillage

open access: yesScientific African, 2023
Oil spillage is one of the major problems in the Niger Delta region of Nigeria, which have affected human health and aquaculture. There is a need to estimate the volume of spill per incidence.
M.I. Ekum, E.E.E. Akarawak, M.O. Adamu
doaj   +1 more source

Detecting epistasis via Markov bases [PDF]

open access: yes, 2010
Rapid research progress in genotyping techniques have allowed large genome-wide association studies. Existing methods often focus on determining associations between single loci and a specific phenotype.
Malaspinas, Anna-Sapfo, Uhler, Caroline
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

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