Results 41 to 50 of about 416,763 (259)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Error Probability Analysis of a Composite Weibull/Log-Normal Fading Channel

open access: yesGazi Üniversitesi Fen Bilimleri Dergisi, 2019
In this study, error probability of a single-input single-output (SISO) system is investigated over a composite Weibull/log-normal fading channel. We aim to study a SISO system in the composite Weibull/log-normal composite fading model which is useful in
Mehmet BİLİM
doaj   +1 more source

Particle size and its distribution deduced from magnetic properties of magnetite nanoparticles by the modified Langevin equation

open access: yesAIP Advances, 2023
The magnetic hysteresis curve can provide information about magnetic properties, particle size, and its distribution. For superparamagnetic materials, the characteristics of the hysteresis curve are very typical, that is, Hc is equal to zero with a ...
Togar Saragi   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Mis-specification effects on mean and model choice: A comparison of log-normal and log-logistic distributions

open access: yesAin Shams Engineering Journal
The log-normal and log-logistic distributions are frequently used to model positively skewed data. Despite the availability of numerous model selection techniques, the risk of mis-specification between these two closely related models remains substantial.
Ramendra Yadav   +3 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

PEMILIHAN DISTRIBUSI PROBABILITAS PADA ANALISA HUJAN DENGAN METODE GOODNESS OF FIT TEST

open access: yesJurnal Teknik Sipil dan Perencanaan, 2016
Rainfall event is a stochastic process, so to explain and analyze this processes the probability theory and frequency analysisare used. There are four types of probability distributions.They are normal, log normal, log Pearson III and Gumbel. To find the
Togani Cahyadi Upomo, Rini Kusumawardani
doaj  

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