MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts
Advanced Science, EarlyView.We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang +5 more
wiley +1 more source
Pareto exponentiated log-logistic distribution (PELL) with an application to Covid-19 data
AIP AdvancesRecently, the Covid-19 pandemic has caused tremendous trauma over the world, leading to psychological and behavioral harm in addition to social and economic instabilities.
Shumaila Ihtisham +4 more
doaj +1 more source
Modelling the COVID-19 Mortality Rate with a New Versatile Modification of the Log-Logistic Distribution. [PDF]
Comput Intell Neurosci, 2021 Muse AH +5 more
europepmc +1 more source
A note on empirical sample distribution of journal impact factors in major discipline groups [PDF]
What type of statistical distribution do the Journal Impact Factors follow? In the past, researchers have hypothesized various types of statistical distributions underlying the generation mechanism of journal impact factors. These are: lognormal, normal,
Mishra, SK
core +1 more source
Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis
Advanced Science, EarlyView.This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu +4 more
wiley +1 more source
Austrian Journal of Statistics, 2016 In this paper we assume that the life time of a test unit follows a log-logistic distribution with known scale parameter. Tables of optimum times of changing stress level for simple step-stress plans under a cumulative exposure model are obtained by ...
Abedel-Qader Al-Masri +1 more
doaj +1 more source
Double and group acceptance sampling plan for truncated life test based on inverse log-logistic distribution. [PDF]
J Appl Stat, 2021 Tripathi H, Dey S, Saha M.
europepmc +1 more source
Characterization of Metastatic Tumor Formation by the Colony Size Distribution
, 2006 Knowledge regarding the kinetics of metastatic tumor formation, as related to the growth of the primary tumor, represents a fundamental issue in cancer biology.
Lee, Steve P. +4 more
core
On Transmuted Four Parameters Generalized Log-Logistic Distribution [PDF]
International Journal of Statistical Distributions and Applications, 2019 In this article we transmute the four parameters generalized log-logistic distribution using quadratic rank transmutation map to develop a transmuted four parameters generalized log-logistic distribution. The quadratic rank transmutation map helps to introduce extra parameter into the baseline distribution to enhance more flexibility in the analysis of
openaire +1 more source
Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation
Advanced Science, EarlyView.Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong +13 more
wiley +1 more source