Results 31 to 40 of about 185,563 (292)

On HT-convexity and Hadamard-type inequalities

open access: yesJournal of Inequalities and Applications, 2020
In the paper, the authors define a new notion of “HT-convex function”, present some Hadamard-type inequalities for the new class of HT-convex functions and for the product of any two HT-convex functions, and derive some inequalities for the arithmetic ...
Shu-Ping Bai, Shu-Hong Wang, Feng Qi
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

THE MEAN SQUARE OF THE LOGARITHM OF THE ZETA-FUNCTION [PDF]

open access: yesGlasgow Mathematical Journal, 2000
For \(\sigma>1/2\) and ...
Balazard, Michel, Ivić, Aleksandar
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

The logarithmic mean is mean

open access: yesMathematical communications, 1997
The fact that the logarithmic mean of two positive numbers is a mean, that is, that it lies between those two numbers, is shown to have a number of consequences.
Mond, Bertram   +2 more
openaire   +2 more sources

Best Possible Inequalities between Generalized Logarithmic Mean and Classical Means

open access: yesAbstract and Applied Analysis, 2010
We answer the question: for α,β,γ∈(0,1) with α+β+γ=1, what are the greatest value p and the least value q, such that the double inequality Lp(a,b)
Yu-Ming Chu, Bo-Yong Long
doaj   +1 more source

Emergy-based indicators of the environmental impacts and driving forces of non-point source pollution from crop production in China

open access: yesEcological Indicators, 2021
Sustainable crop production is a significant challenge in China. To achieve this goal, it is necessary to evaluate environmental impacts related to the sustainable development of crop production by integrating scientific and practical indicators ...
Zuoxi Liu   +11 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Characterization of Monotone Sequences of Positive Numbers Prescribed by Means

open access: yesMathematics
The aim of this article is to investigate the relations between the exponent of the convergence of sequences and other characteristics defined for monotone sequences of positive numbers.
János T. Tóth   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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