Results 191 to 200 of about 44,276 (294)

Amplification through local critical behavior in the mammalian cochlea. [PDF]

Proc Natl Acad Sci U S A
Alonso RG, Gianoli F, Fabella B, Hudspeth AJ.   +3 more
europepmc   +1 more source

Hydroxyl radical footprinting modification reveals an intradomain communication pathway in EFL1 disrupted by a Shwachman‐Diamond syndrome‐associated mutation

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Shwachman‐Diamond syndrome (SDS) is a rare genetic disorder characterized by pancreatic insufficiency and neutropenia. While most cases are linked to mutations in the SBDS gene, some involve mutations in the GTPase EFL1. This protein works with SBDS to release the anti‐association factor eIF6 from the 60S ribosomal subunit during ribosome ...
Jonathan A. Zúñiga‐Domínguez, Rohit Jain, Martín González‐Andrade, Erik R. Farquhar, Mark R. Chance, Abril Gijsbers, Nuria Sánchez‐Puig   +6 more
wiley   +1 more source

Supervised learning of protein variant effects across large‐scale mutagenesis datasets

Protein Science, Volume 35, Issue 4, April 2026.
Abstract The increasing availability of data from multiplexed assays of variant effects (MAVEs) enables supervised model training against large quantities of experimental data to learn sequence‐function relationships. Variant effect scores from MAVEs can, however, be influenced by the experimental method and library composition, resulting in experiment‐
Thea K. Schulze, Lasse M. Blaabjerg, Matteo Cagiada, Kresten Lindorff‐Larsen   +3 more
wiley   +1 more source

Multi-Modal Joint Pulsed Eddy Current Sensor Signal Denoising Method Integrating Inductive Disturbance Mechanism. [PDF]

Sensors (Basel)
Zuo Y, Hu G, Gan F, Zeng Z, Lin Z, Wang X, Xu R, Wen L, Hu S, Le H, Wu R, Wang J.   +11 more
europepmc   +1 more source

Sensitivity to demethylation‐inhibiting fungicides and induced expression of CYP51 associated with tebuconazole resistance in Alternaria species on mandarin in Brazil

Pest Management Science, Volume 82, Issue 4, Page 3663-3676, April 2026.
Tebuconazole‐resistant isolates overexpress CYP51 and, when tested at field rates, did not reduce ABS severity, whereas difenoconazole and mefentrifluconazole remained effective. Abstract BACKGROUND Alternaria brown spot (ABS), caused by Alternaria spp., is an important disease affecting mandarin production in several citrus‐growing regions worldwide ...
Thiago de Aguiar Carraro, Yong Luo, Boris X. Camiletti, Themis J. Michailides, Victor Gabri, Geraldo José Silva‐Junior, Lilian Amorim, Louise Larissa May De Mio   +7 more
wiley   +1 more source

Backpropagation Neural Network-Based Prediction Model of Marble Surface Quality Cut by Diamond Wire Saw. [PDF]

Micromachines (Basel)
Dong H, Cui F, Huo Z, Gao Y.
europepmc   +1 more source

Unraveling Charging and Discharging Processes in Organic Radical‐Based Electrodes: A Hierarchical Molecular and Quantum Mechanical Approach

ChemSusChem, Volume 19, Issue 6, 27 March 2026.
Charge transfer processes are investigated in p‐type organic electrode materials utilizing stable organic radicals incorporated in a conjugated backbone. Molecular dynamics simulations and time‐dependent density functional theory calculations allow us to evaluate charge transfer states as well as the underlying structure–property relationships. Organic
Clara Zens, Georgina E. Shillito, Christian Friebe, Stephan Kupfer   +3 more
wiley   +1 more source

Mechanism and Molecular Design Principles of Cationic Surfactants: From Charge‐Driven Membrane Interactions to Next‐Generation Quaternary Ammonium Compounds

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Within this review we provide an overview of the social relevance of quaternary ammonium surfactants, different classes of these agents, their interaction mechanism with cellular membranes, structure activity relation, bacterial resistance toward these systems and new approaches to guarantee their long‐term efficiency.
Natalie Hanheiser, Yuhang Jiang, Chuanxiong Nie, Rainer Haag   +3 more
wiley   +1 more source

Computerised analysis of non-conjugate spiral bevel gear mesh using an advanced and fast-converging tooth contact model. [PDF]

Sci Rep
Temirkhan M, Amrin A.
europepmc   +1 more source

Exploring the Therapeutic Potential of Cannabidiol in Cutaneous Squamous Cell Carcinoma: An Integrated Computational and Experimental Study

International Journal of Quantum Chemistry, Volume 126, Issue 5, March 5, 2026.
Cannabidiol (CBD) exhibits increased reactivity, stronger CB1 receptor binding, and enhanced cytotoxicity against A431 squamous carcinoma cells compared to 5‐fluorouracil (5‐FU). Integrated DFT, molecular docking, and experimental analyses demonstrate CBD's improved stability and binding affinity, highlighting its potential as an alternative ...
Andrea Jess Josiah, Krishna Kuben Govender, Penny Poomani Govender, Werner Cordier, Margo Nell, Suprakas Sinha Ray   +5 more
wiley   +1 more source