Results 91 to 100 of about 1,206,493 (389)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Can timber provision from Amazonian production forests be sustainable? [PDF]

open access: yes, 2019
Around 30 Mm3 of sawlogs are extracted annually by selective logging of natural production forests in Amazonia, Earth's most extensive tropical forest.
Ascarrunz, Nataly   +23 more
core   +4 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Two-dimensional NMR characterization of gas–water distribution in tight sandstone reservoirs: a case study from the Ordos Basin, China

open access: yesFrontiers in Earth Science
Tight sandstone reservoirs exhibit low porosity, low permeability, significant heterogeneity, and complex gas-water distribution patterns, posing significant challenges for conventional logging methods in accurate gas reservoir identification. Incomplete
Ran Zhang   +11 more
doaj   +1 more source

Logging cuts the functional importance of invertebrates in tropical rainforest

open access: yesNature Communications, 2015
Invertebrates are dominant species in primary tropical rainforests, where their abundance and diversity contributes to the functioning and resilience of these globally important ecosystems.
R. Ewers   +29 more
semanticscholar   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

A training needs analysis for the New Zealand forestry industry : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Psychology at Massey University [PDF]

open access: yes, 2000
Forestry work is inherently dangerous, and logging workers are injured and killed at work at a rate considerably higher than other occupations. A training needs analysis was conducted for the New Zealand Forestry Industry to: identify if there were any ...
Moffat, Helen Patricia
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Log Evaluation Method and Application of Shale Oil Reservoir in Bongor Basin

open access: yesCejing jishu
The evaluation of the main shale oil reservoir in the Baobab block of the Bongor basin, Chad, is insufficient, and a comprehensive method for shale oil resource evaluation is urgently needed.
ZHANG Lihua   +5 more
doaj   +1 more source

The ethics of forgetting in an age of pervasive computing [PDF]

open access: yes, 2005
In this paper, we examine the potential of pervasive computing to create widespread sousveillance, that will complement surveillance, through the development of lifelogs; socio-spatial archives that document every action, every event, every ...
Dodge, M., Kitchin, R.
core  

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