Results 91 to 100 of about 61,101 (268)

Inverting log blowups in log geometry

Tunisian Journal of Mathematics
40 pages.
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Application of Dipole Acoustic Logging Imaging Technology in Fine Description of Reservoir

Cejing jishu
In order to identify the faults, natural fractures along the horizontal well and its distribution between wells in shale oil and gas reservoir, the rich information from the dipole acoustic logging is utilized.
LI Fanhua, SUN Xuekai, ZHANG Tao, YANG Daxiang, SHI Qiang, KAN Hongge, YANG Shihe, GOU Yanhong   +7 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Application of Semi-Permanently Installed Optical Fiber Outside the Tubing in Offshore Heavy Oil Steam Huff and Puff Thermal Recovery Blocks

Cejing jishu
In the heavy oil steam huff and puff thermal recovery blocks of Yuedong island, Liaohe oilfield, dynamic monitoring of production profiles in individual wells is required.
CHI Ming, CHEN Jianbo, WANG Haipeng, ZHAO Yun, WANG Guiyu, ZHAO Yungang, WANG Xiaolong, WANG Longxiang   +7 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Oriented Perforation Techniques with Avoidance of Optical Fibers in Horizontal Wells and Its Application

Cejing jishu
When directional perforating operations are carried out in horizontal wells, the direction is usually achieved by installing a tilted weight in the perforating gun.
HE Hongmin, SUN Zhizhong, HU Yong, JIAO Yan, CHEN Bo, LIU Yachun, NONG Shaozhong   +6 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Analysis of Skin-Oriented Effect Characteristics in Porous Media

Cejing jishu
To clarify the regulatory mechanism of the skin effect in porous media under multiple influencing factors and address the resulting limitation on electromagnetic detection accuracy, a parametric digital rock model of porous media is developed using the ...
WU Jie, ZHAO Bingqian, BAI Yan, TIAN Dou, LIU Shuo   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source