Results 131 to 140 of about 80,361 (310)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Gamma Density Logging Study Based on Sliding Energy Window [PDF]

open access: yes
To reduce the impact of gap fillings (mud cakes) on measurement results in γ density logging and improve logging accuracy, a sliding energy window method is studied based on the positive correlation between mud cake thickness, density, and peak shift ...
ZHANG Qingmin   +5 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Logging response prediction of high-lithium coal seam based on K-means clustering algorithm

open access: yesFrontiers in Earth Science
Lithium in coal, as a new type of associated mineral resource, has considerable potential for exploration. Exploration of high-lithium coal seams is essential for developing and using the associated lithium resources.
Xiwei Mu   +11 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Analisis Yuridis Terhadap Tindakan Pidana Illegal Loging Di Kawasan Hutan Indonesia

open access: yesIBLAM Law Review
Illegal logging merupakan kegiatan penebangan, pengangkutan, dan penjualan kayu yang tidak sah dan tidak memiliki izin terhadap otoritas setempat. Illegal logging menjadi penyebab terbesar kerusakan hutan di Indonesia.
Feny Windiyastuti, Arrum Budi Leksono
doaj   +1 more source

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