Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
A survey on life logging data capturing [PDF]
With the recent availability of inexpensive wearable sensing technologies, the emergence and of both off-line and on-line digital-storage capacity and an acceptance of personal data gathering and online social sharing (timeline), life logging has become ...
Gurrin, Cathal, Zhou, Lijuan Marissa
core +3 more sources
Investigation of Cutter–Woodchip Contact Pressure in a New Biomass Comminution System
A Crumbler® rotary shear system was recently developed to process fuel-grade woodchips into feedstocks having more uniform particle sizes for improved flowability and higher thermochemical output yield than a traditional hammer mill.
Lianshan Lin +3 more
doaj +1 more source
Hydrolysis as a basis for processing vegetable waste into bioplastics [PDF]
The greening of processing waste from logging and woodworking industries involves measures to prevent the negative impact of production processes on the natural environment and is enabled by the development of resource-saving techniques that minimize ...
Ilalova Guzel +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Trends and Perspectives in the Design of Mobile Wood Chippers
Mobile wood chippers represent a mature technology now available in a wide range of sizes and configurations. Different types exist, but the most widespread are disc and drum chippers. The latter have enjoyed wider popularity in recent years because they
Raffaele Spinelli, Enrico Marchi
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Impacts of amending bauxite residue sands with residue fines for the establishment of vegetation on residue disposal areas [PDF]
Long term storage of bauxite residue materials requires a capping stratum which will limit erosion while stabilizing slopes, limit deep infiltration of water into storage piles, and be aesthetically acceptable to the surrounding community.
Anderson, Jonathan
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Costs, CO2 emissions and energy balances of applying Nordic slash recovery methods in British Columbia [PDF]
This paper evaluates the costs, CO2 emissions and energy balances associated with three potential systems for recovering roadside slash in British Columbia, Canada, in which the biomass is transported as slash, hogfuel or bundles.
Sowlati, Taraneh +2 more
core +1 more source

