Results 71 to 80 of about 1,698 (252)

Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

open access: yesAdvanced Science, EarlyView.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin   +3 more
wiley   +1 more source

Feasibility study of logging-while-drilling boundary detection using electric dipole antenna

open access: yesFrontiers in Earth Science
The critical need for deep boundary detection in complex hydrocarbon reservoirs drives the advancement of Logging-while-drilling (LWD) azimuthal electromagnetic measurement (AEM). New deep detection tools employ open-loop half-circle electric dipole (ED)
Changhong Fan   +9 more
doaj   +1 more source

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li   +17 more
wiley   +1 more source

A theoretical analysis of the logging-while-drilling dipole acoustic reflection measurement

open access: yesFrontiers in Earth Science
Post-drilling wireline acoustic single-well imaging technology can now detect geological structures tens of meters away from boreholes. Further development of this single-well imaging technology in the logging-while-drilling (LWD) environment will have ...
Yanghu Li   +5 more
doaj   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

Monopole Acoustic Logging While Drilling Acoustic Insulator Based on Labyrinthine Grooved Structure

open access: yesCejing jishu
In acoustic logging while drilling (ALWD), the presence of a thick-walled drill collar inspires significant amplitude drill collar waves, which will interfere with the measurement and acquisition of formation information.
DOU Yifan, ZHANG Chao, GUAN Wei
doaj   +1 more source

Donor–Acceptor Covalent Organic Framework Enables Ambipolar Charge Storage in Aluminum‐Ion Energy Storage

open access: yesAdvanced Energy Materials, EarlyView.
A donor–acceptor covalent organic framework is designed as an ambipolar cathode for aluminum‐ion energy storage. The crystalline, microporous architecture enables intrinsic charge transport without conductive additives. Multi‐electron redox activity at donor and acceptor sites supports high capacity, excellent stability, and efficient reversible ...
Cataldo Valentini   +11 more
wiley   +1 more source

Multi-scale intelligent fusion and dynamic validation for high-resolution seismic data processing in drilling

open access: yesPetroleum Exploration and Development
During drilling operations, the low resolution of seismic data often limit the accurate characterization of small-scale geological bodies near the borehole and ahead of the drill bit.
Sanyi YUAN   +4 more
doaj   +1 more source

A review of mud pulse telemetry signal impairments modeling and suppression methods

open access: yesJournal of Petroleum Exploration and Production Technology, 2018
Exploration and drilling operations are the most costly and risky activities that require logging while drilling effective tool operation and high speed real-time data transmission.
Saleh M. Mwachaka   +2 more
doaj   +1 more source

Pricing Dynamics in the US Hemp Market: A Vertical Price Transmission Analysis of the Hemp Value Chain

open access: yesAgribusiness, EarlyView.
ABSTRACT The US hemp market is a new and nascent industry that has been devoid of research for about half a century. This study examined the effects of exogenous shock on price at each phase of the value chain—Farm (hemp biomass), and its impact on prices at other phases of the value chain—Intermediary Processor (crude cannabidiol hemp) and Final ...
Solomon Odiase   +2 more
wiley   +1 more source

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