Results 231 to 240 of about 856,531 (293)

Scaffold RNA Reengineering for a Leakage‐Suppressed CRISPR/Cas12a Cascade System Toward Precise Nucleic Acid Diagnostics

Advanced Science, EarlyView.
Schematic illustration of the CALCas system, in which a conformational switch in the 3' terminal DNA extension of scaffold RNA (3'D‐SR) drives cascade‐activatable Cas12a cleavage while suppressing leakage. ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid ...
Xingrong Li, Honghua Hu, Xinli Jiang, Xuhuai Fu, Lin Hu, Qinghua Wu, Jiatong Chai, Diangeng Li, Jinhong Guo, Zhiqiang Li, Yi Li, Yirong Li   +11 more
wiley   +1 more source

Dual-Band All-Optical Logic Gates by Coherent Absorption in an Amorphous Silicon Graphene Metasurface. [PDF]

Nanomaterials (Basel)
Chen Y, Shen C, Li Q, Li J, Deng X.
europepmc   +1 more source

A Chiral Virus‐Like Nanoplatform That Broadly Mediates Antibiotic Delivery to the Brain for Bacterial Meningitis Therapy

Advanced Science, EarlyView.
Chiral virus‐mimicking mesoporous silica nanostructures (CVSNs) efficiently transport diverse antibiotics across the blood–brain barrier (BBB) into brain parenchyma and cerebrospinal fluid. By enhancing delivery to microglia and astrocytes, CVSNs improve antibiotic bioavailability and therapeutic efficacy against both Gram‐negative and Gram‐positive ...
Qianqian Xu, Xuting Zheng, Huinan Tong, Ying Liu, Xiaoxi Fan, Miao Xu, Ziyan Zhang, Li Zhang, Mingyan Liu, Ting Du, Heran Li, Guojun Liu   +11 more
wiley   +1 more source

Magnetoelectric Multiferroics for the Next‐Generation Ultralow‐Power Electronics

Advanced Science, EarlyView.
Magnetoelectric coupling provides a unifying route from electric‐field control of magnetic order to non‐volatile MeRAM, MESO logic, and emerging antiferromagnetic and magnonic devices. By connecting switching physics with device benchmarks, material platforms, and integration strategies, distinctive technological opportunities are identified alongside ...
Yang Liu, Yunlong Sun, Hao Luo, Duoduo Zhao, Yuhan Zeng, Xuzihan Zhang, Zhewei Liu, Hao Peng, Zhijing Zhang, Jack Yang, Ji Zhang, Danyang Wang, Junjie Shi, Sean Li   +13 more
wiley   +1 more source

Quantized Analog Inference Hardware Enabled by MoS2–Hf1‐xZrxO2 FeFET Synapses

Advanced Science, EarlyView.
A monolayer MoS2–HZO FeFET is presented as a pulse‐engineered neuromorphic device suitable for crossbar‐based analog computing. Programming‐pulse design enables tunable conductance trajectories for synaptic weight updates, while quantized machine‐learning approaches account for device variation, nonlinearity, and write noise, translating analog ...
Jeongmin Park, Moonyoung Jung, Hyo‐Bae Kim, Chanhyuk Park, Seohyun Lee, Ki Kang Kim, Hongkee Yoon, Ji‐Hoon Ahn, Dongseok Suh   +8 more
wiley   +1 more source

Multiscale Regulation of Ru‐Based Catalysts for Upgrading Biomass‐Derived Levulinic Acid and Levulinates to γ‐Valerolactone: Mechanisms, Advances, and Challenges

Advanced Science, EarlyView.
This review summarizes recent advances in the mechanistic, thermodynamic, and kinetic studies of biomass‐derived levulinic acid/levulinates conversion to γ‐valerolactone, along with the corresponding multiscale regulation strategies of Ru‐based catalysts.
Xin Ni, Cailu Xiao, Gongbing Zhou, Jingzi Zhang   +3 more
wiley   +1 more source

From Artificial to Embodied and Physical Intelligence in Smart Manufacturing

Advanced Science, EarlyView.
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang, Xinyu Lu, Tong Liu, Jinjie Fang, Xin Li, Siqian Wu, Liuchao Jin, Wei‐Hsin Liao, Shuyou Zhang, Jianrong Tan   +9 more
wiley   +1 more source

Spatiotemporally Precise Rheumatoid Arthritis Therapy via a Triple‐Locked Cascaded Nanoplatform With Dual‐Channel Self‐Reporting

Advanced Science, EarlyView.
An orthogonally programmable nanotheranostic (MB@YW NPs) enables precision therapy for rheumatoid arthritis. A triple‐locked (pH, HOCl/ONOO−, light) independently drives the release of methotrexate and sulfasalazine. Trackable by dual‐channel fluorescence, this coordinated drug delivery remodels the inflammatory microenvironment to markedly suppress ...
Jihong Liu, Wendi Zhu, Shiyun Xu, Shichang Liu, Wenjun Tang, Xiaoyu Ma, Ting Yang, Haojian Yang, Hongtong Wang, Lu Cao, Lijie Tan, Qi Wang   +11 more
wiley   +1 more source

Ferrocene probe-assisted fluorescence quenching of PEI-carbon dots for NO detection and the logic gates based sensing of NO enabled by trimodal detection. [PDF]

Sci Rep
Priya S, Berchmans S.
europepmc   +1 more source